Publications

2024

Seep, Lea; Grein, Stephan; Splichalova, Iva; Ran, Danli; Mikhael, Mickel; Hildebrand, Staffan; Lauterbach, Mario; Hiller, Karsten; Ribeiro, Dalila Juliana Silva; Sieckmann, Katharina; Kardinal, Ronja; Huang, Hao; Yu, Jiangyan; Kallabis, Sebastian; Behrens, Janina; Till, Andreas; Peeva, Viktoriya; Strohmeyer, Akim; Bruder, Johanna; Blum, Tobias; Soriano-Arroquia, Ana; Tischer, Dominik; Kuellmer, Katharina; Li, Yuanfang; Beyer, Marc; Gellner, Anne-Kathrin; Fromme, Tobias; Wackerhage, Henning; Klingenspor, Martin; Fenske, Wiebke K.; Scheja, Ludger; Meissner, Felix; Schlitzer, Andreas; Mass, Elvira; Wachten, Dagmar; Latz, Eicke; Pfeifer, Alexander; Hasenauer, Jan: From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists. Scientific Data 11 (1), 2024 more…

2023

Deline, Marshall L.; Straub, Joshua; Patel, Manisha; Subba, Pratigya; Grashei, Martin; van Heijster, Frits H. A.; Pirkwieser, Philip; Somoza, Veronika; Livingstone, James D.; Beazely, Michael; Kendall, Brian; Gingras, Michel J. P.; Leonenko, Zoya; Höschen, Carmen; Harrington, Gertraud; Kuellmer, Katharina; Bian, Wangqing; Schilling, Franz; Fisher, Matthew P. A.; Helgeson, Matthew E.; Fromme, Tobias: Lithium isotopes differentially modify mitochondrial amorphous calcium phosphate cluster size distribution and calcium capacity. Frontiers in Physiology 14, 2023 more…
Fromme, Theo; Tintrop, Lucie K.; Reichenberger, Sven; Schmidt, Torsten C.; Barcikowski, Stephan: Impact of Chemical and Physical Properties of Organic Solvents on the Gas and Hydrogen Formation during Laser Synthesis of Gold Nanoparticles. ChemPhysChem 24 (11), 2023 more…
Krumm, Johannes; Petrova, Elissaveta; Lechner, Severin; Mergner, Julia; Boehm, Hans-Henning; Prestipino, Alessandro; Steinbrunn, Dominik; Deline, Marshall L.; Koetzner, Lisa; Schindler, Christina; Helming, Laura; Fromme, Tobias; Klingenspor, Martin; Hahne, Hannes; Pieck, Jan-Carsten; Kuster, Bernhard: High-Throughput Screening and Proteomic Characterization of Compounds Targeting Myeloid-Derived Suppressor Cells. Molecular & Cellular Proteomics 22 (9), 2023, 100632 more…
Lechner, Severin; Steimbach, Raphael R.; Wang, Longlong; Deline, Marshall L.; Chang, Yun-Chien; Fromme, Tobias; Klingenspor, Martin; Matthias, Patrick; Miller, Aubry K.; Médard, Guillaume; Kuster, Bernhard: Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid. Nature Communications 14 (1), 2023 more…
Lechner, Severin; Steimbach, Raphael R.; Wang, Longlong; Deline, Marshall L.; Chang, Yun-Chien; Fromme, Tobias; Klingenspor, Martin; Matthias, Patrick; Miller, Aubry K.; Médard, Guillaume; Kuster, Bernhard: Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid. Nature Communications 14 (1), 2023 more…
U-Din, Mueez; Rebelos, Eleni; Saari, Teemu; Niemi, Tarja; Kuellmer, Katharina; Eskola, Olli; Fromme, Tobias; Rajander, Johan; Taittonen, Markku; Klingenspor, Martin; Nuutila, Pirjo; Nummenmaa, Lauri; Virtanen, Kirsi A.: Thermogenic Capacity of Human Supraclavicular Brown Fat and Cold-Stimulated Brain Glucose Metabolism. Metabolites 13 (3), 2023, 387 more…
U-Din, Mueez; de Mello, Vanessa D.; Tuomainen, Marjo; Raiko, Juho; Niemi, Tarja; Fromme, Tobias; Klåvus, Anton; Gautier, Nadine; Haimilahti, Kimmo; Lehtonen, Marko; Kristiansen, Karsten; Newman, John W.; Pietiläinen, Kirsi H.; Pihlajamäki, Jussi; Amri, Ez-Zoubir; Klingenspor, Martin; Nuutila, Pirjo; Pirinen, Eija; Hanhineva, Kati; Virtanen, Kirsi A.: Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans. Cell Reports 42 (9), 2023, 113131 more…

2022

Oeckl, Josef; Janovska, Petra; Adamcova, Katerina; Bardova, Kristina; Brunner, Sarah; Dieckmann, Sebastian; Ecker, Josef; Fromme, Tobias; Funda, Jiri; Gantert, Thomas; Giansanti, Piero; Hidrobo, Maria Soledad; Kuda, Ondrej; Kuster, Bernhard; Li, Yongguo; Pohl, Radek; Schmitt, Sabine; Schweizer, Sabine; Zischka, Hans; Zouhar, Petr; Kopecky, Jan; Klingenspor, Martin: Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat. Molecular Metabolism 61, 2022, 101499 more…

2021

Bast‐Habersbrunner, Andrea; Kiefer, Christoph; Weber, Peter; Fromme, Tobias; Schießl, Anna; Schwalie, Petra C; Deplancke, Bart; Li, Yongguo; Klingenspor, Martin: LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis. EMBO reports 22 (7), 2021 more…
Gantert, Thomas; Henkel, Fiona; Wurmser, Christine; Oeckl, Josef; Fischer, Lena; Haid, Mark; Adamski, Jerzy; Esser‐von Bieren, Julia; Klingenspor, Martin; Fromme, Tobias: Fibroblast growth factor induced Ucp1 expression in preadipocytes requires PGE2 biosynthesis and glycolytic flux. The FASEB Journal 35 (5), 2021 more…
Wang, Hui; Willershäuser, Monja; Li, Yongguo; Fromme, Tobias; Schnabl, Katharina; Bast-Habersbrunner, Andrea; Ramisch, Samira; Mocek, Sabine; Klingenspor, Martin: Uncoupling protein-1 expression does not protect mice from diet-induced obesity. American Journal of Physiology-Endocrinology and Metabolism 320 (2), 2021, E333-E345 more…

2020

Dieckmann, Sebastian; Maurer, Stefanie; Fromme, Tobias; Colson, Cécilia; Virtanen, Kirsi A.; Amri, Ez-Zoubir; Klingenspor, Martin: Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue. Frontiers in Endocrinology 11, 2020 more…
Maurer, Stefanie F.; Dieckmann, Sebastian; Lund, Jens; Fromme, Tobias; Hess, Anne Lundby; Colson, Cécilia; Kjølbæk, Louise; Astrup, Arne; Gillum, Matthew Paul; Larsen, Lesli Hingstrup; Liebisch, Gerhard; Amri, Ez‐Zoubir; Klingenspor, Martin: No Effect of Dietary Fish Oil Supplementation on the Recruitment of Brown and Brite Adipocytes in Mice or Humans under Thermoneutral Conditions. Molecular Nutrition & Food Research 65 (2), 2020, 2000681 more…
Maurer, Stefanie F.; Fromme, Tobias; Mocek, Sabine; Zimmermann, Anika; Klingenspor, Martin: Uncoupling protein 1 and the capacity for nonshivering thermogenesis are components of the glucose homeostatic system. American Journal of Physiology-Endocrinology and Metabolism 318 (2), 2020, E198-E215 more…
Oeckl, Josef; Bast-Habersbrunner, Andrea; Fromme, Tobias; Klingenspor, Martin; Li, Yongguo: Isolation, Culture, and Functional Analysis of Murine Thermogenic Adipocytes. STAR Protocols 1 (3), 2020, 100118 more…
Schöttl, Theresa; Pachl, Fiona; Giesbertz, Pieter; Daniel, Hannelore; Kuster, Bernhard; Fromme, Tobias; Klingenspor, Martin: Proteomic and Metabolite Profiling Reveals Profound Structural and Metabolic Reorganization of Adipocyte Mitochondria in Obesity. Obesity 28 (3), 2020, 590-600 more…

2019

Fromme, Tobias; Hüttinger, Kristina; Maurer, Stefanie; Li, Yongguo; Gantert, Thomas; Fiamoncini, Jarlei; Daniel, Hannelore; Westphal, Sören; Klingenspor, Martin: Bile acid supplementation decreases body mass gain in C57BL/6J but not 129S6/SvEvTac mice without increasing energy expenditure. Scientific Reports 9 (1), 2019 more…
Li, Yongguo; Schwalie, Petra C.; Bast-Habersbrunner, Andrea; Mocek, Sabine; Russeil, Julie; Fromme, Tobias; Deplancke, Bart; Klingenspor, Martin: Systems-Genetics-Based Inference of a Core Regulatory Network Underlying White Fat Browning. Cell Reports 29 (12), 2019, 4099-4113.e5 more…
Mengue N’dille GPR, Biyiti LF, Fromme T, Essame Oyono JL, Klingenspor M: Ethanolic extract of Iwong (Ipomoea alba L., Convolvulaceae) attenuates Adipogenesis in 3T3-L1 adipocytes. International Journal of Herbal Medicine 7 (1), 2019, 11-17 more…
Westphal S, Gantert T, Kless C, Hüttinger K, Klingenspor M, Fromme T.: Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Scientific Reports 9 (1), 2019 more…

2018

Fromme, Tobias; Kleigrewe, Karin; Dunkel, Andreas; Retzler, Angelika; Li, Yongguo; Maurer, Stefanie; Fischer, Natascha; Diezko, Rolf; Kanzleiter, Timo; Hirschberg, Verena; Hofmann, Thomas; Klingenspor, Martin: Degradation of brown adipocyte purine nucleotides regulates uncoupling protein 1 activity. Molecular Metabolism 8, 2018, 77-85 more…
Li, Yongguo; Schnabl, Katharina; Gabler, Sarah-Madeleine; Willershäuser, Monja; Reber, Josefine; Karlas, Angelos; Laurila, Sanna; Lahesmaa, Minna; u Din, Mueez; Bast-Habersbrunner, Andrea; Virtanen, Kirsi A.; Fromme, Tobias; Bolze, Florian; O’Farrell, Libbey S.; Alsina-Fernandez, Jorge; Coskun, Tamer; Ntziachristos, Vasilis; Nuutila, Pirjo; Klingenspor, Martin: Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation. Cell 175 (6), 2018, 1561-1574.e12 more…
Schweizer, Sabine; Oeckl, Josef; Klingenspor, Martin; Fromme, Tobias: Substrate fluxes in brown adipocytes upon adrenergic stimulation and uncoupling protein 1 ablation. Life Science Alliance 1 (6), 2018, e201800136 more…
U Din, Mueez; Saari, Teemu; Raiko, Juho; Kudomi, Nobu; Maurer, Stefanie F.; Lahesmaa, Minna; Fromme, Tobias; Amri, Ez-Zoubir; Klingenspor, Martin; Solin, Olof; Nuutila, Pirjo; Virtanen, Kirsi A.: Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis. Cell Metabolism 28 (2), 2018, 207-216.e3 more…
Wang, Hui; Willershäuser, Monja; Karlas, Angelos; Gorpas, Dimitris; Reber, Josefine; Ntziachristos, Vasilis; Maurer, Stefanie; Fromme, Tobias; Li, Yongguo; Klingenspor, Martin: A dual Ucp1 reporter mouse model for imaging and quantitation of brown and brite fat recruitment. Molecular Metabolism, 2018 more…

2017

Gerngroß, Carlos; Schretter, Johanna; Klingenspor, Martin; Schwaiger, Markus; Fromme, Tobias: Active Brown Fat During 18 F-FDG PET/CT Imaging Defines a Patient Group with Characteristic Traits and an Increased Probability of Brown Fat Redetection. Journal of Nuclear Medicine 58 (7), 2017, 1104-1110 more…
Tews, D.; Fromme, T.; Keuper, M.; Hofmann, S.M.; Debatin, K.M.; Klingenspor, M.; Wabitsch, M.; Fischer-Posovszky, P.: Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells. Molecular and Cellular Endocrinology 443, 2017, 106-113 more…

2016

Li, Y., Fromme, T., Klingenspor, M.: Meaningful respirometric measurements of UCP1-mediated thermogenesis. Biochimie, 2016 more…
Tews, D., Fromme, T., Keuper, M., Hofmann, S.M., Debatin, K.M., Klingenspor, M., Wabitsch, M., Fischer-Posovszky, P.: Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells. Molecular and Cellular Endocrinology, 2016 more…