Immunology
CD8+ T cells are a key component in the naturally occurring immune protection against viral and many bacterial infections and against malignant diseases. My laboratory aims to unravel new molecular mechanisms and strategies to more effectively engage T cells for prophylactic and therapeutic purposes. On this basis we seek to develop new treatment options for diseases in humans and livestock.
Furthermore, we investigate how immune cells impact organ physiology and how they contribute to pathophysiological processes. To this end, we utilize a combination of genomics, systems biology, cellular immunology and molecular cell biology.