Evaluation of Kinase Activity Profiling Using Chemical Proteomics: It has been suggested that the binding of kinases to affinity beads reflects a kinase’s activation status, a concept that is under considerable debate.
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J. D. Berndt and W. Wong, 2014: Signaling Breakthroughs of the Year. Sci. Signal. 8, eg1 (2015).
Citation from the full text:
"Every year, we receive nominations for breakthrough methods that address difficult biological questions. New technologies not only facilitate research but also provide…
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