Dr. Polina Prokofeva

Martín Moyano, Paula; Kubina, Tadeáš; Paruch, Štěpán Owen; Jarošková, Aneta; Novotný, Jan; Skočková, Veronika; Ovesná, Petra; Suchánková, Tereza; Prokofeva, Polina; Kuster, Bernhard; Šmída, Michal; Chaikuad, Apirat; Kramer, Andreas; Knapp, Stefan; Souček, Karel; Paruch, Kamil: Thieno[3,2‐b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode. Angewandte Chemie International Edition, 2024 more…

Kücükdisli, Murat; Bel-Abed, Hassen; Cirillo, Davide; Lo, Wen-Ting; Efrém, Nina-Louisa; Horatscheck, André; Perepelittchenko, Liudmila; Prokofeva, Polina; Ehret, Theresa A. L.; Radetzki, Silke; Neuenschwander, Martin; Specker, Edgar; Médard, Guillaume; Müller, Susanne; Wilhelm, Stephanie; Kuster, Bernhard; von Kries, Jens Peter; Haucke, Volker; Nazaré, Marc: Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition. Journal of Medicinal Chemistry, 2023 more…
Zecha, Jana; Bayer, Florian P.; Wiechmann, Svenja; Woortman, Julia; Berner, Nicola; Müller, Julian; Schneider, Annika; Kramer, Karl; Abril-Gil, Mar; Hopf, Thomas; Reichart, Leonie; Chen, Lin; Hansen, Fynn M.; Lechner, Severin; Samaras, Patroklos; Eckert, Stephan; Lautenbacher, Ludwig; Reinecke, Maria; Hamood, Firas; Prokofeva, Polina; Vornholz, Larsen; Falcomatà, Chiara; Dorsch, Madeleine; Schröder, Ayla; Venhuizen, Anton; Wilhelm, Stephanie; Médard, Guillaume; Stoehr, Gabriele; Ruland, Jürgen; Grüner, Barbara M.; Saur, Dieter; Buchner, Maike; Ruprecht, Benjamin; Hahne, Hannes; The, Matthew; Wilhelm, Mathias; Kuster, Bernhard: Decrypting drug actions and protein modifications by dose- and time-resolved proteomics. Science 380 (6640), 2023, 93-101 more…

Lechner, Severin; Malgapo, Martin Ian P.; Grätz, Christian; Steimbach, Raphael R.; Baron, Agnes; Rüther, Patrick; Nadal, Simon; Stumpf, Carmen; Loos, Christina; Ku, Xin; Prokofeva, Polina; Lautenbacher, Ludwig; Heimburg, Tino; Würf, Vivian; Meng, Chen; Wilhelm, Mathias; Sippl, Wolfgang; Kleigrewe, Karin; Pauling, Josch K.; Kramer, Karl; Miller, Aubry K.; Pfaffl, Michael W.; Linder, Maurine E.; Kuster, Bernhard; Médard, Guillaume: Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target. Nature Chemical Biology, 2022 more…
Lo, Wen-Ting; Belabed, Hassane; Kücükdisli, Murat; Metag, Juliane; Roske, Yvette; Prokofeva, Polina; Ohashi, Yohei; Horatscheck, André; Cirillo, Davide; Krauss, Michael; Schmied, Christopher; Neuenschwander, Martin; von Kries, Jens Peter; Médard, Guillaume; Kuster, Bernhard; Perisic, Olga; Williams, Roger L.; Daumke, Oliver; Payrastre, Bernard; Severin, Sonia; Nazaré, Marc; Haucke, Volker: Development of selective inhibitors of phosphatidylinositol 3-kinase C2α. Nature Chemical Biology, 2022 more…
Prokofeva, Polina; Höfer, Stefanie; Hornisch, Maximilian; Abele, Miriam; Kuster, Bernhard; Médard, Guillaume: Merits of Diazirine Photo-Immobilization for Target Profiling of Natural Products and Cofactors. ACS Chemical Biology, 2022 more…

DR. POLINA PROKOFEVA