2025
- Cold-induced phosphatidylethanolamine synthesis in liver and brown adipose tissue of mice. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1870 (1), 2025, 159562 mehr…
2024
- Mechanisms involved in the muscle relaxing effects of STW 5 in guinea pig stomach. Neurogastroenterology & Motility, 2024 mehr…
- Mitochondrial lipidomes are tissue specific – low cholesterol contents relate to UCP1 activity. Life Science Alliance 7 (8), 2024, e202402828 mehr…
- Single-cell transcriptome analysis reveals secretin as a hallmark of human enteroendocrine cell maturation. Scientific Reports 14 (1), 2024 mehr…
- From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists. Scientific Data 11 (1), 2024 mehr…
2023
- Effects of Fatty Acid Metabolites on Adipocytes Britening: Role of Thromboxane A2. Cells 12 (3), 2023, 446 mehr…
- Lithium isotopes differentially modify mitochondrial amorphous calcium phosphate cluster size distribution and calcium capacity. Frontiers in Physiology 14, 2023 mehr…
- Impact of Chemical and Physical Properties of Organic Solvents on the Gas and Hydrogen Formation during Laser Synthesis of Gold Nanoparticles. ChemPhysChem 24 (11), 2023 mehr…
- High-Throughput Screening and Proteomic Characterization of Compounds Targeting Myeloid-Derived Suppressor Cells. Molecular & Cellular Proteomics 22 (9), 2023, 100632 mehr…
- Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid. Nature Communications 14 (1), 2023 mehr…
- Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid. Nature Communications 14 (1), 2023 mehr…
- Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development. Nature Immunology 24 (3), 2023, 501-515 mehr…
- Secretin modulates appetite via brown adipose tissue-brain axis. European Journal of Nuclear Medicine and Molecular Imaging 50 (6), 2023, 1597-1606 mehr…
- Thermogenic Capacity of Human Supraclavicular Brown Fat and Cold-Stimulated Brain Glucose Metabolism. Metabolites 13 (3), 2023, 387 mehr…
- Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans. Cell Reports 42 (9), 2023, 113131 mehr…
- The negative adipogenesis regulator Dlk1 is transcriptionally regulated by Ifrd1 (TIS7) and translationally by its orthologue Ifrd2 (SKMc15). eLife 12, 2023 mehr…
2022
- Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1. American Journal of Physiology-Endocrinology and Metabolism 322 (2), 2022, E85-E100 mehr…
- Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat. Molecular Metabolism 61, 2022, 101499 mehr…
2021
- LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis. EMBO reports 22 (7), 2021 mehr…
- Spatial Recruitment of Cardiolipins in Inguinal White Adipose Tissue after Cold Stimulation is Independent of UCP1. European Journal of Lipid Science and Technology, 2021, 2100090 mehr…
- Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography. Molecular Metabolism 47, 2021, 101184 mehr…
- Fibroblast growth factor induced Ucp1 expression in preadipocytes requires PGE2 biosynthesis and glycolytic flux. The FASEB Journal 35 (5), 2021 mehr…
- Secretin activates brown fat and induces satiation. Nature Metabolism 3 (6), 2021, 798-809 mehr…
- Revisiting energy expenditure: how to correct mouse metabolic rate for body mass. Nature Metabolism 3 (9), 2021, 1134-1136 mehr…
- Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists. Molecular Metabolism 49, 2021, 101181 mehr…
- Secretin as a Satiation Whisperer With the Potential to Turn into an Obesity-curbing Knight. Endocrinology 162 (9), 2021 mehr…
- Protein Kinase D2 drives chylomicron‐mediated lipid transport in the intestine and promotes obesity. EMBO Molecular Medicine 13 (5), 2021 mehr…
- Uncoupling protein-1 expression does not protect mice from diet-induced obesity. American Journal of Physiology-Endocrinology and Metabolism 320 (2), 2021, E333-E345 mehr…
2020
- A Phenotyping Platform to Characterize Healthy Individuals Across Four Stages of Life - The Enable Study. Frontiers in Nutrition 7, 2020 mehr…
- Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue. Frontiers in Endocrinology 11, 2020 mehr…
- The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation. Nature Communications 11 (1), 2020 mehr…
- Meltome atlas—thermal proteome stability across the tree of life. Nature Methods 17 (5), 2020, 495-503 mehr…
- Submucosal enteric neurons of the cavine distal colon are sensitive to hypoosmolar stimuli. The Journal of Physiology 598 (23), 2020, 5317-5332 mehr…
- Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes. Journal of Hepatology 73 (6), 2020, 1347-1359 mehr…
- No Effect of Dietary Fish Oil Supplementation on the Recruitment of Brown and Brite Adipocytes in Mice or Humans under Thermoneutral Conditions. Molecular Nutrition & Food Research 65 (2), 2020, 2000681 mehr…
- Uncoupling protein 1 and the capacity for nonshivering thermogenesis are components of the glucose homeostatic system. American Journal of Physiology-Endocrinology and Metabolism 318 (2), 2020, E198-E215 mehr…
- Isolation, Culture, and Functional Analysis of Murine Thermogenic Adipocytes. STAR Protocols 1 (3), 2020, 100118 mehr…
- Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment. Science Translational Medicine 12 (565), 2020, eaay7019 mehr…
- The gut hormone secretin triggers a gut-brown fat-brain axis in the control of food intake. Experimental Physiology, 2020 mehr…
- Proteomic and Metabolite Profiling Reveals Profound Structural and Metabolic Reorganization of Adipocyte Mitochondria in Obesity. Obesity 28 (3), 2020, 590-600 mehr…
2019
- Bile acid supplementation decreases body mass gain in C57BL/6J but not 129S6/SvEvTac mice without increasing energy expenditure. Scientific Reports 9 (1), 2019 mehr…
- Secretin Links Brown Fat to Food Intake: New Perspectives for Targeting Energy Balance in Humans. Obesity 27 (6), 2019, 875-877 mehr…
- Systems-Genetics-Based Inference of a Core Regulatory Network Underlying White Fat Browning. Cell Reports 29 (12), 2019, 4099-4113.e5 mehr…
- Ethanolic extract of Iwong (Ipomoea alba L., Convolvulaceae) attenuates Adipogenesis in 3T3-L1 adipocytes. International Journal of Herbal Medicine 7 (1), 2019, 11-17 mehr…
- High-Fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett’s Esophagus via Interleukin 8 and Alterations to the Gut Microbiome. Gastroenterology 157 (2), 2019, 492-506.e2 mehr…
- High-fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett’s Esophagus via IL8 and Alterations to the Gut Microbiome. Gastroenterology, 2019 mehr…
- Opposing Actions of Adrenocorticotropic Hormone and Glucocorticoids on UCP1-Mediated Respiration in Brown Adipocytes. Frontiers in Physiology 9, 2019 mehr…
- The lipidome of primary murine white, brite, and brown adipocytes—Impact of beta-adrenergic stimulation. PLOS Biology 17 (8), 2019, e3000412 mehr…
- Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency. Journal of Inherited Metabolic Disease, 2019 mehr…
- Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Experimental Eye Research, 2019 mehr…
- Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Experimental Eye Research, 2019 mehr…
- Adipose Mitochondrial Respiratory Capacity in Obesity is Impaired Independently of Glycemic Status of Tissue Donors. Obesity, 2019 mehr…
- Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Scientific Reports 9 (1), 2019 mehr…
2018
- Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data. PLOS Biology 16 (4), 2018, e2005019 mehr…
- The exceptional sensitivity of brain mitochondria to copper. Toxicology in Vitro 51, 2018, 11-22 mehr…
- Degradation of brown adipocyte purine nucleotides regulates uncoupling protein 1 activity. Molecular Metabolism 8, 2018, 77-85 mehr…
- Impact of dietary ω3 polyunsaturated fatty acid supplementation on brown and brite adipocyte function. Journal of Lipid Research, 2018, jlr.M081091 mehr…
- Brown adipocyte glucose metabolism: a heated subject. EMBO reports 19 (9), 2018, e46404 mehr…
- A mouse model for intellectual disability caused by mutations in the X-linked 2′‑O‑methyltransferase Ftsj1 gene. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2018 mehr…
- Animal models of obesity and diabetes mellitus. Nature Reviews Endocrinology 14 (3), 2018, 140-162 mehr…
- Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation. Cell 175 (6), 2018, 1561-1574.e12 mehr…
- Fatty Acid Metabolites as Novel Regulators of Non-shivering Thermogenesis. In: Handbook of Experimental Pharmacology. Springer Berlin Heidelberg, 2018 mehr…
- Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain. Scientific Reports 8 (1), 2018 mehr…
- Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Nature Communications 9 (1), 2018 mehr…
- Substrate fluxes in brown adipocytes upon adrenergic stimulation and uncoupling protein 1 ablation. Life Science Alliance 1 (6), 2018, e201800136 mehr…
- Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis. Cell Metabolism 28 (2), 2018, 207-216.e3 mehr…
- A dual Ucp1 reporter mouse model for imaging and quantitation of brown and brite fat recruitment. Molecular Metabolism, 2018 mehr…
2017
- Aminoglycosides, but not PTC124 (Ataluren), rescue nonsense mutations in the leptin receptor and in luciferase reporter genes. Scientific Reports 7 (1), 2017 mehr…
- Fgf9 Y162C Mutation Alters Information Processing and Social Memory in Mice. Molecular Neurobiology, 2017 mehr…
- Active Brown Fat During 18 F-FDG PET/CT Imaging Defines a Patient Group with Characteristic Traits and an Increased Probability of Brown Fat Redetection. Journal of Nuclear Medicine 58 (7), 2017, 1104-1110 mehr…
- Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863 (6), 2017, 1605-1614 mehr…
- Proximate causes for diet-induced obesity in laboratory mice: a case study. European Journal of Clinical Nutrition 71 (3), 2017, 306-317 mehr…
- A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice. Molecular Psychiatry, 2017 mehr…
- Meis1 : effects on motor phenotypes and the sensorimotor system in mice. Disease Models & Mechanisms 10 (8), 2017, 981-991 mehr…
- Metformin causes a futile intestinal–hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state. Molecular Metabolism 6 (7), 2017, 737-747 mehr…
- Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells. Molecular and Cellular Endocrinology 443, 2017, 106-113 mehr…
2016
- Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice. Journal of Inherited Metabolic Disease 39 (2), 2016, 309-319 mehr…
- Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms. Molecular Neurobiology, 2016, 1-21 mehr…
- Control of adipogenesis by oxylipins, GPCRs and PPARs. Biochimie, 2016 mehr…
- Mitochondrial function controls intestinal epithelial stemness and proliferation. Nature Communications 7, 2016 mehr…
- Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation. Diabetologia 59 (9), 2016, 2005-2012 mehr…
- Long-acting PASylated leptin ameliorates obesity by promoting satiety and preventing hypometabolism in leptin-deficient Lepob/ob mice. Endocrinology 157 (1), 2016, 233-244 mehr…
- Long-Acting PASylated Leptin Ameliorates Obesity by Promoting Satiety and Preventing Hypometabolism in Leptin-DeficientLepob/obMice. Endocrinology 157 (1), 2016, 233-244 mehr…
- Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice. Journal of breath research 10 (1), 2016, 016009 mehr…
- Generation of Mice Lacking DUF1220 Protein Domains: Effects on Fecundity and Hyperactivity. Mammalian Genome 26 (1-2), 2016, 33-42 mehr…
- Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice. Journal of Breath Research 10 (1), 2016 mehr…
- Generation and standardized, systemic phenotypic analysis of Pou3f3L423P mutant mice. PLoS ONE 11 (3), 2016 mehr…
- Dietary fat and gut microbiota interactions determine diet-induced obesity in mice. Molecular Metabolism 5 (12), 2016, 1162-1174 mehr…
- Meaningful respirometric measurements of UCP1-mediated thermogenesis. Biochimie, 2016 mehr…
- Reduced mitochondrial mass and function add to age-related susceptibility toward diet-induced fatty liver in C57BL/6J mice. Physiological Reports 4 (19), 2016 mehr…
- The first Scube3 mutant mouse line with pleiotropic phenotypic alterations. G3: Genes, Genomes, Genetics 6 (12), 2016, 4035-4046 mehr…
- Viable Ednra Y129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation. Mammalian Genome 27 (11-12), 2016, 587-598 mehr…
- Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells. Molecular and Cellular Endocrinology, 2016 mehr…
2015
- eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription. Nature Communications 6, 2015 mehr…
- Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics. Nature Genetics 47 (9), 2015, 969-978 mehr…
- Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers. Genome Research 25 (9), 2015, 1295-1308 mehr…
- Inverse relationship between body mass index and mitochondrial oxidative phosphorylation capacity in human subcutaneous adipocytes. American Journal of Physiology - Endocrinology and Metabolism 309 (4), 2015, E380-E387 mehr…
- Diet-induced obesity causes metabolic impairment independent of alterations in gut barrier integrity. Molecular Nutrition and Food Research 59 (5), 2015, 968-978 mehr…
- Glucose tolerance tests for systematic screening of glucose homeostasis in mice. Current protocols in mouse biology 5 (1), 2015, 65-84 mehr…
- The brown and brite adipocyte marker Cox7a1 is not required for non-shivering thermogenesis in mice. Scientific Reports 5, 2015 mehr…
- PASylation of murine leptin leads to extended plasma half-life and enhanced in vivo efficacy. Molecular Pharmaceutics 12 (5), 2015, 1431-1442 mehr…
- Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 156 (3), 2015, 923-933 mehr…
- Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Molecular Metabolism 4 (9), 2015, 631-642 mehr…
- The development of diet-induced obesity and associated metabolic impairments in Dj-1 deficient mice. Journal of Nutritional Biochemistry 26 (1), 2015, 75-81 mehr…
2014
- Leveraging cross-species transcription factor binding site patterns: From diabetes risk loci to disease mechanisms. Cell 156 (1-2), 2014, 343-358 mehr…
- Generation of Mice Lacking DUF1220 Protein Domains: Effects on Fecundity and Hyperactivity. Mammalian Genome 26 (1-2), 2014, 33-42 mehr…
- Effects of diet-matrix on volatile organic compounds in breath in diet-induced obese mice. Journal of Breath Research 8 (1), 2014 mehr…
- Mitochondrial DNA variants in obesity. PLoS ONE 9 (5), 2014 mehr…
- Pleiotropic functions for transcription factor Zscan10. PLoS ONE 9 (8), 2014 mehr…
- Raw coffee based dietary supplements contain carboxyatractyligenin derivatives inhibiting mitochondrial adenine-nucleotide-translocase. Food and Chemical Toxicology 70, 2014, 198-204 mehr…
- Intrinsic differences in BRITE adipogenesis of primary adipocytes from two different mouse strains. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1841 (9), 2014, 1345-1352 mehr…
- Taking control over intracellular fatty acid levels is essential for the analysis of thermogenic function in cultured primary brown and brite/beige adipocytes. EMBO Reports 15 (10), 2014, 1069-1076 mehr…
- White, brite, and brown adipocytes: The evolution and function of a heater organ in mammals1. Canadian Journal of Zoology 92 (7), 2014, 615-626 mehr…
- A review of standardized metabolic phenotyping of animal models. Mammalian Genome 25 (9-10), 2014, 497-507 mehr…
- High-fat diet induced isoform changes of the Parkinson's disease protein DJ-1. Journal of Proteome Research 13 (5), 2014, 2339-2351 mehr…
- Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring. Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 (2), 2014, 304-317 mehr…
- Restless Legs Syndrome-Associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon. Genome Research 24 (4), 2014, 592-603 mehr…
- Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43. Journal of Biological Chemistry 289 (15), 2014, 10769-10784 mehr…
- Online breath gas analysis in unrestrained mice by hs-PTR-MS. Mammalian Genome 25 (3-4), 2014, 129-140 mehr…
- Comparative gene array analysis of progenitor cells from human paired deep neck and subcutaneous adipose tissue. Molecular and Cellular Endocrinology 395 (1-2), 2014, 41-50 mehr…
- Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet. ISME Journal 8 (12), 2014, 2380-2396 mehr…
2013
- Standardized, Systemic Phenotypic Analysis of UmodC93F and UmodA227T Mutant Mice. PLoS ONE 8 (10), 2013 mehr…
- Development of a capillary isoelectric focusing immunoassay to measure DJ-1 isoforms in biological samples. Analytical Biochemistry 443 (2), 2013, 197-204 mehr…
- Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo. Pharmacogenomics Journal 13 (1), 2013, 80-93 mehr…
- Diet-induced obesity in ad libitum-fed mice: Food texture overrides the effect of macronutrient composition. British Journal of Nutrition 109 (8), 2013, 1518-1527 mehr…
- A Functional Nexus between Photoperiod Acclimation, Torpor Expression and Somatic Fatty Acid Composition in a Heterothermic Mammal. PLoS ONE 8 (5), 2013 mehr…
- High Fat Diet Accelerates Pathogenesis of Murine Crohn's Disease-Like Ileitis Independently of Obesity. PLoS ONE 8 (8), 2013 mehr…
- Photoperiod-Dependent Regulation of Carboxypeptidase E Affects the Selective Processing of Neuropeptides in the Seasonal Siberian Hamster (Phodopus sungorus). Journal of Neuroendocrinology 25 (2), 2013, 190-197 mehr…
- A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes. PLoS ONE 8 (12), 2013 mehr…
- A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice. PLoS ONE 8 (11), 2013 mehr…
- Gene Set of Nuclear-Encoded Mitochondrial Regulators Is Enriched for Common Inherited Variation in Obesity. PLoS ONE 8 (2), 2013 mehr…
- 2-O-β-D-Glucopyranosyl-carboxyatractyligenin from Coffea L. inhibits adenine nucleotide translocase in isolated mitochondria but is quantitatively degraded during coffee roasting. Phytochemistry 93, 2013, 124-135 mehr…
- Browning attenuates murine white adipose tissue expansion during postnatal development. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1831 (5), 2013, 960-968 mehr…
- SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities. DNA Repair 12 (5), 2013, 356-366 mehr…
- Rapamycin extends murine lifespan but has limited effects on aging. Journal of Clinical Investigation 123 (8), 2013, 3272-3291 mehr…
- Neuronal Expression of Glucosylceramide Synthase in Central Nervous System Regulates Body Weight and Energy Homeostasis. PLoS Biology 11 (3), 2013 mehr…
- Boosting mitochondrial biogenesis in white adipocytes: A route towards improved insulin sensitivity? Molecular Metabolism 2 (3), 2013, 128-129 mehr…
- FTO deficiency induces UCP-1 expression and mitochondrial uncoupling in adipocytes. Endocrinology 154 (9), 2013, 3141-3151 mehr…
2012
- Rescue of melanocortin 4 receptor (MC4R) nonsense mutations by aminoglycoside-mediated read-through. Obesity 20 (5), 2012, 1074-1081 mehr…
- Innovations in phenotyping of mouse models in the German Mouse Clinic. Mammalian Genome 23 (9-10), 2012, 611-622 mehr…
- Mouse Genetics and Metabolic Mouse Phenotyping. In: Genetics Meets Metabolomics. Springer New York, 2012 mehr…
- Structural features and bioavailability of four flavonoids and their implications for lifespan-extending and antioxidant actions in C. elegans. Mechanisms of Ageing and Development 133 (1), 2012, 1-10 mehr…
- The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis. FASEB Journal 26 (12), 2012, 5081-5091 mehr…
- Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology. FASEB Journal 26 (9), 2012, 3916-3930 mehr…
- Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients. Acta Neuropathologica 124 (2), 2012, 187-197 mehr…
- Functional characterization of UCP1 in mammalian HEK293 cells excludes mitochondrial uncoupling artefacts and reveals no contribution to basal proton leak. Biochimica et Biophysica Acta - Bioenergetics 1817 (9), 2012, 1660-1670 mehr…
- Brown fat develops a brite future. Obesity Facts 5 (6), 2012, 890-896 mehr…
- Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines. European Journal of Oral Sciences 120 (4), 2012, 269-277 mehr…
- Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype. PLoS ONE 7 (7), 2012 mehr…
- Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans. PLoS Genetics 8 (3), 2012 mehr…
- Phylogenetic differences of mammalian basal metabolic rate are not explained by mitochondrial basal proton leak. Proceedings of the Royal Society B: Biological Sciences 279 (1726), 2012, 185-193 mehr…
- Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system. PLoS ONE 7 (6), 2012 mehr…
- Seasonal leptin resistance is associated with impaired signalling via JAK2-STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology 182 (4), 2012, 553-567 mehr…
- Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants. BMC Medical Genomics 5, 2012 mehr…
2011
- A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. Arthritis and Rheumatism 63 (5), 2011, 1301-1311 mehr…
- A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. Arthritis & Rheumatism 63 (5), 2011, 1301-1311 mehr…
- Metabolic phenotyping of the Crohn's disease-like IBD etiopathology in the TNF ΔARE/WT mouse model. Journal of Proteome Research 10 (12), 2011, 5523-5535 mehr…
- Uncoupling protein 1 expression and high-fat diets. American Journal of Physiology - Regulatory Integrative and Comparative Physiology 300 (1), 2011 mehr…
- Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets. Particle and Fibre Toxicology 8, 2011 mehr…
- Test systems to study the structure and function of uncoupling protein 1: A critical overview. Frontiers in Endocrinology 2 (NOV), 2011 mehr…
- Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice. Journal of Biological Chemistry 286 (21), 2011, 18614-18622 mehr…
- Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice. Journal of Biological Chemistry 286 (21), 2011, 18614-18622 mehr…
- Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice. Journal of Biological Chemistry 286 (21), 2011, 18614-18622 mehr…
- Brown Adipose Tissue. In: Adipose Tissue Biology. Springer New York, 2011 mehr…
- Mouse phenotyping. Methods 53 (2), 2011, 120-135 mehr…
- Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells. Nature Communications 2 (1), 2011 mehr…
2010
- Behavioural mechanisms affecting energy regulation in mice prone or resistant to diet- induced obesity. Physiology and Behavior 99 (3), 2010, 370-380 mehr…
- Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice. American Journal of Physiology - Regulatory Integrative and Comparative Physiology 299 (5), 2010 mehr…
- Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 416insG mice. Mammalian Genome 21 (1-2), 2010, 13-27 mehr…
- Two new loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and German study groups. PLoS Genetics 6 (4), 2010 mehr…
- CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice. EMBO Journal 29 (14), 2010, 2421-2432 mehr…
- Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice. PLoS ONE 5 (3), 2010 mehr…
- Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes. Science 328 (5982), 2010, 1158-1161 mehr…
2009
- Mouse models for the central melanocortin system. Genes and Nutrition 4 (2), 2009, 129-134 mehr…
- Proteome Differences between Brown and White Fat Mitochondria Reveal Specialized Metabolic Functions. Cell Metabolism 10 (4), 2009, 324-335 mehr…
- An intronic single base exchange leads to a brown adipose tissue-specific loss of Ucp3 expression and an altered body mass trajectory. Physiological Genomics 38 (1), 2009, 54-62 mehr…
- Systemic first-line phenotyping. Methods in Molecular Biology 530, 2009, 463-509 mehr…
- Photoperiodic regulation of satiety mediating neuropeptides in the brainstem of the seasonal Siberian hamster (Phodopus sungorus). Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology 195 (7), 2009, 631-642 mehr…
- Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis. BMC Evolutionary Biology 9 (1), 2009 mehr…
- Mitochondrial proton conductance in skeletal muscle of a cold-exposed marsupial, Antechinus flavipes, is unlikely to be involved in adaptive nonshivering thermogenesis but displays increased sensitivity toward carbon-centered radicals. Physiological and Biochemical Zoology 82 (5), 2009, 447-454 mehr…
- Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism. American Journal of Physiology - Renal Physiology 297 (5), 2009 mehr…
- Inflammation and mitochondrial fatty acid β-oxidation link obesity to early tumor promotion. Proceedings of the National Academy of Sciences of the United States of America 106 (9), 2009, 3354-3359 mehr…
- The German mouse clinic: A platform for systemic phenotype analysis of mouse models. Current Pharmaceutical Biotechnology 10 (2), 2009, 236-243 mehr…
- Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. PLoS ONE 4 (6), 2009 mehr…
- High energy digestion efficiency and altered lipid metabolism contribute to obesity in BFMI mice. Obesity 17 (11), 2009, 1988-1993 mehr…
- EuroPhenome: A repository for high-throughput mouse phenotyping data. Nucleic Acids Research 38, 2009, D577-D585 mehr…
- EuroPhenome: a repository for high-throughput mouse phenotyping data. Nucleic Acids Research 38 (suppl_1), 2009, D577-D585 mehr…
- A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice. Cell 137 (5), 2009, 961-971 mehr…
- Gene-gene interaction between apoa5 and usf1: Two candidate genes for the metabolic syndrome The KORA group. Obesity Facts 2 (4), 2009, 235-242 mehr…
2008
- 3-Iodothyronamine: A novel hormone controlling the balance between glucose and lipid utilisation. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology 178 (2), 2008, 167-177 mehr…
- Nuclear receptor cofactor receptor interacting protein 140 controls hepatic triglyceride metabolism during wasting in mice. Hepatology 48 (3), 2008, 782-791 mehr…
- A new look at the evolution of uncoupling protein 1-mediated non-shivering thermogenesis. In: Jastroch M, Klingenspor M. Hypometabolism in Animals: Hibernation, torpor and cryobiology. Interpak Books, 2008 mehr…
- Marsupial uncoupling protein 1 sheds light on the evolution of mammalian nonshivering thermogenesis. Physiological Genomics 32 (2), 2008, 161-169 mehr…
- Seasonal regulation of cocaine- and amphetamine-regulated transcript in the arcuate nucleus of Djungarian hamster (Phodopus sungorus). General and Comparative Endocrinology 157 (2), 2008, 142-147 mehr…
- An ancient look at UCP1. Biochimica et Biophysica Acta - Bioenergetics 1777 (7-8), 2008, 637-641 mehr…
- Towards ecological relevance: a comparison of physiological and molecular evidence for the presence of adaptive, UCP1-mediated non-shivering thermogenesis in mammals. In: Mzilikazi N, Meyer CW, Klingenspor M. Hypometabolism in Animals: Hibernation, torpor and cryobiology. Interpak Books, 2008 mehr…
- Brown adipose tissue specific lack of uncoupling protein 3 is associated with impaired cold tolerance and reduced transcript levels of metabolic genes. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology 178 (3), 2008, 269-277 mehr…
- The effects of fasting and cold exposure on metabolic rate and mitochondrial proton leak in liver and skeletal muscle of an amphibian, the cane toad Bufo marinus. Journal of Experimental Biology 211 (12), 2008, 1911-1918 mehr…
2007
- Rapid single step subcloning procedure by combined action of type II and type IIs endonucleases with ligase. Journal of Biological Engineering 1, 2007 mehr…
- Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in Phodopus sungorus. BMC Molecular Biology 8, 2007 mehr…
- Functional characterisation of UCP1 in the common carp: Uncoupling activity in liver mitochondria and cold-induced expression in the brain. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology 177 (7), 2007, 743-752 mehr…
- Power matters in closing the phenotyping gap. Naturwissenschaften 94 (5), 2007, 401-406 mehr…
- Expanding the body mass range: Associations between BMR and tissue morphology in wild type and mutant dwarf mice (David mice). Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology 177 (2), 2007, 183-192 mehr…
- The molecular and biochemical basis of nonshivering thermogenesis in an African endemic mammal, Elephantulus myurus. American Journal of Physiology - Regulatory Integrative and Comparative Physiology 293 (5), 2007 mehr…
- Wheel running affects seasonal acclimatization of physiological and morphological traits in the Djungarian hamster (Phodopus sungorus). American Journal of Physiology - Regulatory Integrative and Comparative Physiology 293 (3), 2007 mehr…
- The role of the IGF-I system for vitellogenesis in maturing female sterlet, Acipenser ruthenus Linnaeus, 1758. General and Comparative Endocrinology 150 (1), 2007, 140-150 mehr…
2006
- Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312 (5774), 2006, 734-737 mehr…
- PC1/3 and PC2 gene expression and post-translational endoproteolytic pro-opiomelanocortin processing is regulated by photoperiod in the seasonal Siberian hamster (Phodopus sungorus). Journal of Neuroendocrinology 18 (6), 2006, 413-425 mehr…
- The suppressor of cytokine signalling 3, SOCS3, may be one critical modulator of seasonal body weight changes in the Siberian hamster, Phodopus sungorus. Journal of Neuroendocrinology 18 (2), 2006, 139-145 mehr…
- Photoperiodic regulation of insulin receptor mRNA and intracellular insulin signaling in the arcuate nucleus of the Siberian hamster, Phodopus sungorus. American Journal of Physiology - Regulatory Integrative and Comparative Physiology 291 (3), 2006 mehr…
2005
- Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis. Physiological Genomics 22, 2005, 150-156 mehr…
- Evidence for Nr4a1 as a cold-induced effector of brown fat thermogenesis. Physiological Genomics 24 (1), 2005, 37-44 mehr…
- Neuronal distribution of melanin-concentrating hormone, cocaine- and amphetamine-regulated transcript and orexin B in the brain of the Djungarian hamster (Phodopus sungorus). Journal of Chemical Neuroanatomy 29 (2), 2005, 137-148 mehr…
- Introducing the German Mouse Clinic: Open access platform for standardized phenotyping. Nature Methods 2 (6), 2005, 403-404 mehr…
- A role for brain-derived neurotrophic factor in B cell development. Journal of Neuroimmunology 163 (1-2), 2005, 15-23 mehr…
2004
- Depression of transcription and translation during daily torpor in the Djungarian hamster (Phodopus sungorus). Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology 174 (6), 2004, 495-502 mehr…
- Uncoupling protein 2 and 3 in marsupials: Identification, phylogeny, and gene expression in response to cold and fasting in Antechinus flavipes. Physiological Genomics 17, 2004, 130-139 mehr…
- Absence of UCP3 in brown adipose tissue does not impair nonshivering thermogenesis. Physiological and Biochemical Zoology 77 (1), 2004, 116-126 mehr…
- Gene or size: Metabolic rate and body temperature in obese growth hormone-deficient dwarf mice. Obesity Research 12 (9), 2004, 1509-1518 mehr…
- A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity. Endocrinology 145 (5), 2004, 2531-2541 mehr…
- Photoperiodic Regulation of Leptin Sensitivity in the Siberian Hamster, Phodopus sungorus, Is Reflected in Arcuate Nucleus SOCS-3 (Suppressor of Cytokine Signaling) Gene Expression. Endocrinology 145 (3), 2004, 1185-1193 mehr…
- Circulating Ghrelin Levels and Central Ghrelin Receptor Expression are Elevated in Response to Food Deprivation in a Seasonal Mammal (Phodopus sungorus). Journal of Neuroendocrinology 16 (11), 2004, 922-928 mehr…
2003
- Normal distribution of body weight gain in male Sprague-Dawley rats fed a high-energy diet. Obesity Research 11 (11), 2003, 1376-1383 mehr…
- Hyperactivity in patients with anorexia nervosa and in semistarved rats: Evidence for a pivotal role of hypoleptinemia. Physiology and Behavior 79 (1), 2003, 25-37 mehr…
- Cold-induced recruitment of brown adipose tissue thermogenesis. Experimental Physiology 88 (1), 2003, 141-148 mehr…
2002
- Differential gene expression in white and brown preadipocytes. Physiological Genomics 2002 (7), 2002, 15-25 mehr…
- Photoperiodic regulation of leptin resistance in the seasonally breeding Siberian hamster (Phodopus sungorus). Endocrinology 143 (8), 2002, 3083-3095 mehr…
- Glucocorticoid hormone stimulates mitochondrial biogenesis specifically in skeletal muscle. Endocrinology 143 (1), 2002, 177-184 mehr…
2001
2000
- Leptin acts on metabolism in a photoperiod-dependent manner, but has no effect on reproductive function in the seasonally breeding Siberian hamster (Phodopus sungorus). Endocrinology 141 (11), 2000, 4128-4135 mehr…
- Leptin suppresses semi-starvation induced hyperactivity in rats: Implications for anorexia nervosa. Molecular Psychiatry 5 (5), 2000, 476-481 mehr…
- Modulation of leptin sensitivity by short photoperiod acclimation in the Djungarian hamster, Phodopus sungorus. Journal of Comparative Physiology - B Biochemical, Systemic, and Environmental Physiology 170 (1), 2000, 37-43 mehr…
- Seasonal thermogenic acclimation of diurnally and nocturnally active desert spiny mice. Physiological and Biochemical Zoology 73 (1), 2000, 37-44 mehr…
1999
- Metabolic adjustments during daily torpor in the Djungarian hamster. American Journal of Physiology - Endocrinology and Metabolism 276 (5 39-5), 1999 mehr…
- Altered gene expression pattern in the fatty liver dystrophy mouse reveals impaired insulin-mediated cytoskeleton dynamics. Journal of Biological Chemistry 274 (33), 1999, 23078-23084 mehr…
1997
- Localization of ubiquitin gene family members to mouse chromosomes 5, 11, and 18. Mammalian Genome 8 (10), 1997, 789-790 mehr…
- Localization of profilin-1 (Pfn1) and a related sequence (Pfn1-rs) to mouse chromosomes 11 and 15 respectively. Mammalian Genome 8 (7), 1997, 539-540 mehr…
- Contrasting adrenergic effects on lipoprotein lipase gene expression in the brown adipose tissue of intact mice and in cultured brown adipocytes from mice. Biochimica et Biophysica Acta - Lipids and Lipid Metabolism 1345 (3), 1997, 327-337 mehr…
1996
- Short photoperiod reduces leptin gene expression in white and brown adipose tissue of Djungarian hamsters. FEBS Letters 399 (3), 1996, 290-294 mehr…
- Multiple regulatory steps are involved in the control of lipoprotein lipase activity in brown adipose tissue. Journal of Lipid Research 37 (8), 1996, 1685-1695 mehr…
- Biogenesis of thermogenic mitochondria in brown adipose tissue of Djungarian hamsters during cold adaptation. Biochemical Journal 316 (2), 1996, 607-613 mehr…
- Perinatal energy stores and excessive fat deposition in genetically obese (fa/fa) rats. American Journal of Physiology - Endocrinology and Metabolism 270 (4 33-4), 1996 mehr…
1994
- Effect of unilateral surgical denervation of brown adipose tissue on uncoupling protein mRNA level and cytochrom-c-oxidase activity in the Djungarian hamster. Journal of Comparative Physiology B 163 (8), 1994, 664-670 mehr…
1991
- Daily torpor in the Djungarian hamster (Phodopus sungorus): interactions with food intake, activity, and social behaviour. Journal of Comparative Physiology B 160 (6), 1991, 609-615 mehr…
1989
- Photoperiod and thermoregulation in vertebrates: body temperature rhythms and thermogenic acclimation. Journal of biological rhythms 4 (2), 1989, 251-265 mehr…
- Short photoperiod and cold activate brown fat lipoprotein lipase in the Djungarian hamster. American Journal of Physiology - Regulatory Integrative and Comparative Physiology 257 (5), 1989 mehr…