Publications

2024

Abbas, Qussai; Wilhelm, Mathias; Kuster, Bernhard; Poppenberger, Brigitte; Frishman, Dmitrij: Exploring crop genomes: assembly features, gene prediction accuracy, and implications for proteomics studies. BMC Genomics 25 (1), 2024 mehr…
Brunner, Sarah; Höring, Marcus; Liebisch, Gerhard; Schweizer, Sabine; Scheiber, Josef; Giansanti, Piero; Hidrobo, Maria; Hermeling, Sven; Oeckl, Josef; Prudente de Mello, Natalia; Perocchi, Fabiana; Seeliger, Claudine; Strohmeyer, Akim; Klingenspor, Martin; Plagge, Johannes; Küster, Bernhard; Burkhardt, Ralph; Janssen, Klaus-Peter; Ecker, Josef: Mitochondrial lipidomes are tissue specific – low cholesterol contents relate to UCP1 activity. Life Science Alliance 7 (8), 2024, e202402828 mehr…
Chang, Yun-Chien; Gnann, Christian; Steimbach, Raphael R.; Bayer, Florian P.; Lechner, Severin; Sakhteman, Amirhossein; Abele, Miriam; Zecha, Jana; Trendel, Jakob; The, Matthew; Lundberg, Emma; Miller, Aubry K.; Kuster, Bernhard: Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics. Cell Reports 43 (6), 2024, 114272 mehr…
Eckert, Stephan; Berner, Nicola; Kramer, Karl; Schneider, Annika; Müller, Julian; Lechner, Severin; Brajkovic, Sarah; Sakhteman, Amirhossein; Graetz, Christian; Fackler, Jonas; Dudek, Michael; Pfaffl, Michael W.; Knolle, Percy; Wilhelm, Stephanie; Kuster, Bernhard: Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics. Nature Biotechnology, 2024 mehr…
Graf, Alina; Bassukas, Alkistis Eleftheria Lanassa; Xiao, Yao; Barbosa, Inês C. R.; Mergner, Julia; Grill, Peter; Michalke, Bernhard; Kuster, Bernhard; Schwechheimer, Claus: D6PK plasma membrane polarity requires a repeated CXX(X)P motif and PDK1-dependent phosphorylation. Nature Plants, 2024 mehr…
Janacek, Dorina P.; Kolb, Martina; Schulz, Lukas; Mergner, Julia; Kuster, Bernhard; Glanc, Matouš; Friml, Jiří; ten Tusscher, Kirsten; Schwechheimer, Claus; Hammes, Ulrich Z.: Transport properties of canonical PIN-FORMED proteins from Arabidopsis and the role of the loop domain in auxin transport. Developmental Cell, 2024 mehr…
Kuster, Bernhard; Tüshaus, Johanna; Bayer, Florian P.: A new mass analyzer shakes up the proteomics field. Nature Biotechnology, 2024 mehr…
Martín Moyano, Paula; Kubina, Tadeáš; Paruch, Štěpán Owen; Jarošková, Aneta; Novotný, Jan; Skočková, Veronika; Ovesná, Petra; Suchánková, Tereza; Prokofeva, Polina; Kuster, Bernhard; Šmída, Michal; Chaikuad, Apirat; Kramer, Andreas; Knapp, Stefan; Souček, Karel; Paruch, Kamil: Thieno[3,2‐b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode. Angewandte Chemie International Edition, 2024 mehr…
Schneider, Carolin; Hilbert, Jorina; Genevaux, Franziska; Höfer, Stefanie; Krauß, Lukas; Schicktanz, Felix; Contreras, Constanza Tapia; Jansari, Shaishavi; Papargyriou, Aristeidis; Richter, Thorsten; Alfayomy, Abdallah M.; Falcomatà, Chiara; Schneeweis, Christian; Orben, Felix; Öllinger, Ruppert; Wegwitz, Florian; Boshnakovska, Angela; Rehling, Peter; Müller, Denise; Ströbel, Philipp; Ellenrieder, Volker; Conradi, Lena; Hessmann, Elisabeth; Ghadimi, Michael; Grade, Marian; Wirth, Matthias; Steiger, Katja; Rad, Roland; Kuster, Bernhard; Sippl, Wolfgang; Reichert, Maximilian; Saur, Dieter; Schneider, Günter: A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction. Advanced Science, 2024 mehr…
Schwalm, Martin P.; Dopfer, Johannes; Kumar, Adarsh; Greco, Francesco A.; Bauer, Nicolas; Löhr, Frank; Heering, Jan; Cano-Franco, Sara; Lechner, Severin; Hanke, Thomas; Jaser, Ivana; Morasch, Viktoria; Lenz, Christopher; Fearon, Daren; Marples, Peter G.; Tomlinson, Charles W. E.; Brunello, Lorene; Saxena, Krishna; Adams, Nathan B. P.; von Delft, Frank; Müller, Susanne; Stolz, Alexandra; Proschak, Ewgenij; Kuster, Bernhard; Knapp, Stefan; Rogov, Vladimir V.: Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets. Nature Communications 15 (1), 2024 mehr…
Sperk, Anna; Gabriel, Antje; Koch, Daniela; Augsburger, Abirami; Sanchez, Victoria; Brockelt, David; Öllinger, Rupert; Engleitner, Thomas; Giansanti, Piero; Ludwig, Romina; Auf der Maur, Priska; Walter, Wencke; Haferlach, Torsten; Jeremias, Irmela; Rad, Roland; Steigenberger, Barbara; Kuster, Bernhard; Eichner, Ruth; Bassermann, Florian: FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells. Leukemia, 2024 mehr…
Stepan, Jens; Heinz, Daniel E.; Dethloff, Frederik; Wiechmann, Svenja; Martinelli, Silvia; Hafner, Kathrin; Ebert, Tim; Junglas, Ellen; Häusl, Alexander S.; Pöhlmann, Max L.; Jakovcevski, Mira; Pape, Julius C.; Zannas, Anthony S.; Bajaj, Thomas; Hermann, Anke; Ma, Xiao; Pavenstädt, Hermann; Schmidt, Mathias V.; Philipsen, Alexandra; Turck, Christoph W.; Deussing, Jan M.; Rammes, Gerhard; Robinson, Andrew C.; Payton, Antony; Wehr, Michael C.; Stein, Valentin; Murgatroyd, Christopher; Kremerskothen, Joachim; Kuster, Bernhard; Wotjak, Carsten T.; Gassen, Nils C.: Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice. Science Signaling 17 (834), 2024 mehr…
The, Matthew; Picciani, Mario; Jensen, Cecilia; Gabriel, Wassim; Kuster, Bernhard; Wilhelm, Mathias: AI-Assisted Processing Pipeline to Boost Protein Isoform Detection. In: Protein Bioinformatics. Springer US, 2024 mehr…
Yoshida, Takuya; Mergner, Julia; Yang, Zhenyu; Liu, Jinghui; Kuster, Bernhard; Fernie, Alisdair R.; Grill, Erwin: Integrating multi‐omics data reveals energy and stress signaling activated by abscisic acid in Arabidopsis. The Plant Journal, 2024 mehr…

2023

Abele, Miriam; Doll, Etienne; Bayer, Florian P.; Meng, Chen; Lomp, Nina; Neuhaus, Klaus; Scherer, Siegfried; Kuster, Bernhard; Ludwig, Christina: Unified workflow for the rapid and in-depth characterization of bacterial proteomes. Molecular & Cellular Proteomics, 2023, 100612 mehr…
Adamowicz, Klaudia; Arend, Lis; Maier, Andreas; Schmidt, Johannes R.; Kuster, Bernhard; Tsoy, Olga; Zolotareva, Olga; Baumbach, Jan; Laske, Tanja: Proteomic meta-study harmonization, mechanotyping and drug repurposing candidate prediction with ProHarMeD. npj Systems Biology and Applications 9 (1), 2023 mehr…
Arfelli, Vanessa C.; Chang, Yun-Chien; Bagnoli, Johannes W.; Kerbs, Paul; Ciamponi, Felipe E.; Paz, Laissa M. da S.; Pankivskyi, Serhii; de Matha Salone, Jean; Maucuer, Alexandre; Massirer, Katlin B.; Enard, Wolfgang; Kuster, Bernhard; Greif, Philipp A.; Archangelo, Leticia Fröhlich: UHMK1 is a novel splicing regulatory kinase. Journal of Biological Chemistry 299 (4), 2023, 103041 mehr…
Bayer, Florian P.; Gander, Manuel; Kuster, Bernhard; The, Matthew: CurveCurator: a recalibrated F-statistic to assess, classify, and explore significance of dose–response curves. Nature Communications 14 (1), 2023 mehr…
Bernhardt, Alexander M.; Tiedt, Steffen; Teupser, Daniel; Dichgans, Martin; Meyer, Bernhard; Gempt, Jens; Kuhn, Peer-Hendrik; Simons, Mikael; Palleis, Carla; Weidinger, Endy; Nübling, Georg; Holdt, Lesca; Hönikl, Lisa; Gasperi, Christiane; Giesbertz, Pieter; Müller, Stephan A.; Breimann, Stephan; Lichtenthaler, Stefan F.; Kuster, Bernhard; Mann, Matthias; Imhof, Axel; Barth, Teresa; Hauck, Stefanie M.; Zetterberg, Henrik; Otto, Markus; Weichert, Wilko; Hemmer, Bernhard; Levin, Johannes: A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases. eBioMedicine 89, 2023, 104456 mehr…
Brajkovic, Sarah; Rugen, Nils; Agius, Carlos; Berner, Nicola; Eckert, Stephan; Sakhteman, Amirhossein; Schwechheimer, Claus; Kuster, Bernhard: Getting Ready for Large-Scale Proteomics in Crop Plants. Nutrients 15 (3), 2023, 783 mehr…
Ecker, Veronika; Brandmeier, Lisa; Stumpf, Martina; Giansanti, Piero; Moreira, Aida Varela; Pfeuffer, Lisa; Fens, Marcel H.A.M.; Lu, Junyan; Kuster, Bernhard; Engleitner, Thomas; Heidegger, Simon; Rad, Roland; Ringshausen, Ingo; Zenz, Thorsten; Wendtner, Clemens-Martin; Müschen, Markus; Jellusova, Julia; Ruland, Jürgen; Buchner, Maike: Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression. Cell Reports 42 (10), 2023, 113017 mehr…
Kardell, Oliver; von Toerne, Christine; Merl-Pham, Juliane; König, Ann-Christine; Blindert, Marcel; Barth, Teresa K.; Mergner, Julia; Ludwig, Christina; Tüshaus, Johanna; Eckert, Stephan; Müller, Stephan A.; Breimann, Stephan; Giesbertz, Pieter; Bernhardt, Alexander M.; Schweizer, Lisa; Albrecht, Vincent; Teupser, Daniel; Imhof, Axel; Kuster, Bernhard; Lichtenthaler, Stefan F.; Mann, Matthias; Cox, Jürgen; Hauck, Stefanie M.: Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens. Journal of Proteome Research, 2023 mehr…
Knecht, Sascha; Eberl, H. Christian; Kreisz, Norbert; Ugwu, Ukamaka Juliet; Starikova, Tatiana; Kuster, Bernhard; Wilhelm, Stephanie: An introduction to analytical challenges, approaches and applications in mass-spectrometry-based secretomics. Molecular & Cellular Proteomics, 2023, 100636 mehr…
Krumm, Johannes; Petrova, Elissaveta; Lechner, Severin; Mergner, Julia; Boehm, Hans-Henning; Prestipino, Alessandro; Steinbrunn, Dominik; Deline, Marshall L.; Koetzner, Lisa; Schindler, Christina; Helming, Laura; Fromme, Tobias; Klingenspor, Martin; Hahne, Hannes; Pieck, Jan-Carsten; Kuster, Bernhard: High-throughput screening and proteomic characterization of compounds targeting myeloid-derived suppressor cells. Molecular & Cellular Proteomics, 2023, 100632 mehr…
Kücükdisli, Murat; Bel-Abed, Hassen; Cirillo, Davide; Lo, Wen-Ting; Efrém, Nina-Louisa; Horatscheck, André; Perepelittchenko, Liudmila; Prokofeva, Polina; Ehret, Theresa A. L.; Radetzki, Silke; Neuenschwander, Martin; Specker, Edgar; Médard, Guillaume; Müller, Susanne; Wilhelm, Stephanie; Kuster, Bernhard; von Kries, Jens Peter; Haucke, Volker; Nazaré, Marc: Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition. Journal of Medicinal Chemistry, 2023 mehr…
Lechner, Severin; Steimbach, Raphael R.; Wang, Longlong; Deline, Marshall L.; Chang, Yun-Chien; Fromme, Tobias; Klingenspor, Martin; Matthias, Patrick; Miller, Aubry K.; Médard, Guillaume; Kuster, Bernhard: Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid. Nature Communications 14 (1), 2023 mehr…
Lee, Chien-Yun; The, Matthew; Meng, Chen; Bayer, Florian P; Putzker, Kerstin; Müller, Julian; Streubel, Johanna; Woortman, Julia; Sakhteman, Amirhossein; Resch, Moritz; Schneider, Annika; Wilhelm, Stephanie; Kuster, Bernhard: Illuminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics. Molecular Systems Biology, 2023 mehr…
Liu, Liping; Trendel, Jakob; Jiang, Guojing; Liu, Yanhui; Bruckmann, Astrid; Küster, Bernhard; Sprunck, Stefanie; Dresselhaus, Thomas; Bleckmann, Andrea: RBPome identification in egg-cell like callus of <i>Arabidopsis</i>. Biological Chemistry 0 (0), 2023 mehr…
Němec, Václav; Khirsariya, Prashant; Janovská, Pavlína; Moyano, Paula Martín; Maier, Lukáš; Procházková, Petra; Kebková, Pavlína; Gybel', Tomáš; Berger, Benedict‐Tilman; Chaikuad, Apirat; Reinecke, Maria; Kuster, Bernhard; Knapp, Stefan; Bryja, Vítězslav; Paruch, Kamil: Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity. Angewandte Chemie 135 (11), 2023 mehr…
Picciani, Mario; Gabriel, Wassim; Giurcoiu, Victor‐George; Shouman, Omar; Hamood, Firas; Lautenbacher, Ludwig; Jensen, Cecilia Bang; Müller, Julian; Kalhor, Mostafa; Soleymaniniya, Armin; Kuster, Bernhard; The, Matthew; Wilhelm, Mathias: Oktoberfest: Open‐source spectral library generation and rescoring pipeline based on Prosit. PROTEOMICS, 2023 mehr…
Reinecke, Maria; Brear, Paul; Vornholz, Larsen; Berger, Benedict-Tilmann; Seefried, Florian; Wilhelm, Stephanie; Samaras, Patroklos; Gyenis, Laszlo; Litchfield, David William; Médard, Guillaume; Müller, Susanne; Ruland, Jürgen; Hyvönen, Marko; Wilhelm, Mathias; Kuster, Bernhard: Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors. Nature Chemical Biology, 2023 mehr…
Rieger, Leonie; Irlinger, Kilian; Fuechsl, Franziska; Barbian, Nicolas; Tietje, Marlene; Faber, Melanie; Schulze, Tobias; Giansanti, Piero; Besse, Lenka; Driessen, Christoph; Krackhardt, Angela; Kuster, Bernhard; Bassermann, Florian: Regulation of BCMA By the Ubiquitin Proteasome System Enables Optimization of BCMA-Targeting Therapies in Multiple Myeloma. Blood 142 (Supplement 1), 2023, 3310-3310 mehr…
Tretter, Celina; de Andrade Krätzig, Niklas; Pecoraro, Matteo; Lange, Sebastian; Seifert, Philipp; von Frankenberg, Clara; Untch, Johannes; Zuleger, Gabriela; Wilhelm, Mathias; Zolg, Daniel P.; Dreyer, Florian S.; Bräunlein, Eva; Engleitner, Thomas; Uhrig, Sebastian; Boxberg, Melanie; Steiger, Katja; Slotta-Huspenina, Julia; Ochsenreither, Sebastian; von Bubnoff, Nikolas; Bauer, Sebastian; Boerries, Melanie; Jost, Philipp J.; Schenck, Kristina; Dresing, Iska; Bassermann, Florian; Friess, Helmut; Reim, Daniel; Grützmann, Konrad; Pfütze, Katrin; Klink, Barbara; Schröck, Evelin; Haller, Bernhard; Kuster, Bernhard; Mann, Matthias; Weichert, Wilko; Fröhling, Stefan; Rad, Roland; Hiltensperger, Michael; Krackhardt, Angela M.: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification. Nature Communications 14 (1), 2023 mehr…
Tröster, Alix; DiPrima, Michael; Jores, Nathalie; Kudlinzki, Denis; Sreeramulu, Sridhar; Gande, Santosh L.; Linhard, Verena; Ludig, Damian; Schug, Alexander; Saxena, Krishna; Reinecke, Maria; Heinzlmeir, Stephanie; Leisegang, Matthias S.; Wollenhaupt, Jan; Lennartz, Frank; Weiss, Manfred S.; Kuster, Bernhard; Tosato, Giovanna; Schwalbe, Harald: Optimization of the Lead Compound NVP‐BHG712 as a Colorectal Cancer Inhibitor. Chemistry – A European Journal 29 (23), 2023 mehr…
Tüshaus, Johanna; Sakhteman, Amirhossein; Lechner, Severin; The, Matthew; Mucha, Eike; Krisp, Christoph; Schlegel, Jürgen; Delbridge, Claire; Kuster, Bernhard: A region‐resolved proteomic map of the human brain enabled by high‐throughput proteomics. The EMBO Journal, 2023 mehr…
Zecha, Jana; Bayer, Florian P.; Wiechmann, Svenja; Woortman, Julia; Berner, Nicola; Müller, Julian; Schneider, Annika; Kramer, Karl; Abril-Gil, Mar; Hopf, Thomas; Reichart, Leonie; Chen, Lin; Hansen, Fynn M.; Lechner, Severin; Samaras, Patroklos; Eckert, Stephan; Lautenbacher, Ludwig; Reinecke, Maria; Hamood, Firas; Prokofeva, Polina; Vornholz, Larsen; Falcomatà, Chiara; Dorsch, Madeleine; Schröder, Ayla; Venhuizen, Anton; Wilhelm, Stephanie; Médard, Guillaume; Stoehr, Gabriele; Ruland, Jürgen; Grüner, Barbara M.; Saur, Dieter; Buchner, Maike; Ruprecht, Benjamin; Hahne, Hannes; The, Matthew; Wilhelm, Mathias; Kuster, Bernhard: Decrypting drug actions and protein modifications by dose- and time-resolved proteomics. Science 380 (6640), 2023, 93-101 mehr…

2022

Bian, Yangyang; Gao, Chunli; Kuster, Bernhard: On the potential of micro-flow LC-MS/MS in proteomics. Expert Review of Proteomics 19 (3), 2022, 153-164 mehr…
Bozilovic, Jelena; Eing, Lorenz; Berger, Benedict-Tilman; Adhikari, Bikash; Weckesser, Janik; Berner, Nicola B.; Wilhelm, Stephanie; Kuster, Bernhard; Wolf, Elmar; Knapp, Stefan: Novel, highly potent PROTACs targeting AURORA-A kinase. Current Research in Chemical Biology 2, 2022, 100032 mehr…
Djukovic, Ana; Garzón, María José; Canlet, Cécile; Cabral, Vitor; Lalaoui, Rym; García-Garcerá, Marc; Rechenberger, Julia; Tremblay-Franco, Marie; Peñaranda, Iván; Puchades-Carrasco, Leonor; Pineda-Lucena, Antonio; González-Barberá, Eva María; Salavert, Miguel; López-Hontangas, José Luis; Sanz, Miguel Á.; Sanz, Jaime; Kuster, Bernhard; Rolain, Jean-Marc; Debrauwer, Laurent; Xavier, Karina B.; Xavier, Joao B.; Ubeda, Carles: Lactobacillus supports Clostridiales to restrict gut colonization by multidrug-resistant Enterobacteriaceae. Nature Communications 13 (1), 2022 mehr…
Falcomatà, Chiara; Bärthel, Stefanie; Widholz, Sebastian A.; Schneeweis, Christian; Montero, Juan José; Toska, Albulena; Mir, Jonas; Kaltenbacher, Thorsten; Heetmeyer, Jeannine; Swietlik, Jonathan J.; Cheng, Jing-Yuan; Teodorescu, Bianca; Reichert, Oliver; Schmitt, Constantin; Grabichler, Kathrin; Coluccio, Andrea; Boniolo, Fabio; Veltkamp, Christian; Zukowska, Magdalena; Vargas, Angelica Arenas; Paik, Woo Hyun; Jesinghaus, Moritz; Steiger, Katja; Maresch, Roman; Öllinger, Rupert; Ammon, Tim; Baranov, Olga; Robles, Maria S.; Rechenberger, Julia; Kuster, Bernhard; Meissner, Felix; Reichert, Maximilian; Flossdorf, Michael; Rad, Roland; Schmidt-Supprian, Marc; Schneider, Günter; Saur, Dieter: Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment. Nature Cancer 3 (3), 2022, 318-336 mehr…
Gabriel, Wassim; The, Matthew; Zolg, Daniel P.; Bayer, Florian P.; Shouman, Omar; Lautenbacher, Ludwig; Schnatbaum, Karsten; Zerweck, Johannes; Knaute, Tobias; Delanghe, Bernard; Huhmer, Andreas; Wenschuh, Holger; Reimer, Ulf; Médard, Guillaume; Kuster, Bernhard; Wilhelm, Mathias: Prosit-TMT: Deep Learning Boosts Identification of TMT-Labeled Peptides. Analytical Chemistry 94 (20), 2022, 7181-7190 mehr…
Giansanti, Piero; Samaras, Patroklos; Bian, Yangyang; Meng, Chen; Coluccio, Andrea; Frejno, Martin; Jakubowsky, Hannah; Dobiasch, Sophie; Hazarika, Rashmi R.; Rechenberger, Julia; Calzada-Wack, Julia; Krumm, Johannes; Mueller, Sebastian; Lee, Chien-Yun; Wimberger, Nicole; Lautenbacher, Ludwig; Hassan, Zonera; Chang, Yun-Chien; Falcomatà, Chiara; Bayer, Florian P.; Bärthel, Stefanie; Schmidt, Tobias; Rad, Roland; Combs, Stephanie E.; The, Matthew; Johannes, Frank; Saur, Dieter; de Angelis, Martin Hrabe; Wilhelm, Mathias; Schneider, Günter; Kuster, Bernhard: Mass spectrometry-based draft of the mouse proteome. Nature Methods 19 (7), 2022, 803-811 mehr…
Glas, Carina; Naydenova, Eli; Lechner, Severin; Wössner, Nathalie; Yang, Liu; Dietschreit, Johannes C.B.; Sun, Hongyan; Jung, Manfred; Kuster, Bernhard; Ochsenfeld, Christian; Bracher, Franz: Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition. European Journal of Medicinal Chemistry 240, 2022, 114594 mehr…
Hamood, Firas; Bayer, Florian P.; Wilhelm, Mathias; Kuster, Bernhard; The, Matthew: SIMSI-Transfer: Software-assisted reduction of missing values in phosphoproteomic and proteomic isobaric labeling data using tandem mass spectrum clustering. Molecular & Cellular Proteomics, 2022, 100238 mehr…
Hanke, Thomas; Mathea, Sebastian; Woortman, Julia; Salah, Eidarus; Berger, Benedict-Tilman; Tumber, Anthony; Kashima, Risa; Hata, Akiko; Kuster, Bernhard; Müller, Susanne; Knapp, Stefan: Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes. Journal of Medicinal Chemistry 65 (19), 2022, 13264-13287 mehr…
Krumm, Johannes; Sekine, Keisuke; Samaras, Patroklos; Brazovskaja, Agnieska; Breunig, Markus; Yasui, Ryota; Kleger, Alexander; Taniguchi, Hideki; Wilhelm, Mathias; Treutlein, Barbara; Camp, J. Gray; Kuster, Bernhard: High temporal resolution proteome and phosphoproteome profiling of stem cell-derived hepatocyte development. Cell Reports 38 (13), 2022, 110604 mehr…
Lechner, Severin; Malgapo, Martin Ian P.; Grätz, Christian; Steimbach, Raphael R.; Baron, Agnes; Rüther, Patrick; Nadal, Simon; Stumpf, Carmen; Loos, Christina; Ku, Xin; Prokofeva, Polina; Lautenbacher, Ludwig; Heimburg, Tino; Würf, Vivian; Meng, Chen; Wilhelm, Mathias; Sippl, Wolfgang; Kleigrewe, Karin; Pauling, Josch K.; Kramer, Karl; Miller, Aubry K.; Pfaffl, Michael W.; Linder, Maurine E.; Kuster, Bernhard; Médard, Guillaume: Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target. Nature Chemical Biology, 2022 mehr…
Lier, Svenja; Sellmer, Andreas; Orben, Felix; Heinzlmeir, Stephanie; Krauß, Lukas; Schneeweis, Christian; Hassan, Zonera; Schneider, Carolin; Patricia Gloria Schäfer, Arlett; Pongratz, Herwig; Engleitner, Thomas; Öllinger, Rupert; Kuisl, Anna; Bassermann, Florian; Schlag, Christoph; Kong, Bo; Dove, Stefan; Kuster, Bernhard; Rad, Roland; Reichert, Maximilian; Wirth, Matthias; Saur, Dieter; Mahboobi, Siavosh; Schneider, Günter: A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer. Bioorganic Chemistry 119, 2022, 105505 mehr…
Lo, Wen-Ting; Belabed, Hassane; Kücükdisli, Murat; Metag, Juliane; Roske, Yvette; Prokofeva, Polina; Ohashi, Yohei; Horatscheck, André; Cirillo, Davide; Krauss, Michael; Schmied, Christopher; Neuenschwander, Martin; von Kries, Jens Peter; Médard, Guillaume; Kuster, Bernhard; Perisic, Olga; Williams, Roger L.; Daumke, Oliver; Payrastre, Bernard; Severin, Sonia; Nazaré, Marc; Haucke, Volker: Development of selective inhibitors of phosphatidylinositol 3-kinase C2α. Nature Chemical Biology, 2022 mehr…
Mergner, Julia; Kuster, Bernhard: Plant Proteome Dynamics. Annual Review of Plant Biology 73 (1), 2022, 67-92 mehr…
Oeckl, Josef; Janovska, Petra; Adamcova, Katerina; Bardova, Kristina; Brunner, Sarah; Dieckmann, Sebastian; Ecker, Josef; Fromme, Tobias; Funda, Jiri; Gantert, Thomas; Giansanti, Piero; Hidrobo, Maria Soledad; Kuda, Ondrej; Kuster, Bernhard; Li, Yongguo; Pohl, Radek; Schmitt, Sabine; Schweizer, Sabine; Zischka, Hans; Zouhar, Petr; Kopecky, Jan; Klingenspor, Martin: Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat. Molecular Metabolism 61, 2022, 101499 mehr…
Orben, Felix; Lankes, Katharina; Schneeweis, Christian; Hassan, Zonera; Jakubowsky, Hannah; Krauß, Lukas; Boniolo, Fabio; Schneider, Carolin; Schäfer, Arlett; Murr, Janine; Schlag, Christoph; Kong, Bo; Öllinger, Rupert; Wang, Chengdong; Beyer, Georg; Mahajan, Ujjwal M.; Xue, Yonggan; Mayerle, Julia; Schmid, Roland M.; Kuster, Bernhard; Rad, Roland; Braun, Christian J.; Wirth, Matthias; Reichert, Maximilian; Saur, Dieter; Schneider, Günter: Epigenetic drug screening defines a PRMT5 inhibitor–sensitive pancreatic cancer subtype. JCI Insight 7 (10), 2022 mehr…
Paulmann, Carmen; Spallek, Ria; Karpiuk, Oleksandra; Heider, Michael; Schäffer, Isabell; Zecha, Jana; Klaeger, Susan; Walzik, Michaela; Öllinger, Rupert; Engleitner, Thomas; Wirth, Matthias; Keller, Ulrich; Krönke, Jan; Rudelius, Martina; Kossatz, Susanne; Rad, Roland; Kuster, Bernhard; Bassermann, Florian: The <scp>OTUD6B‐LIN28B‐MYC</scp> axis determines the proliferative state in multiple myeloma. The EMBO Journal 41 (20), 2022 mehr…
Prokofeva, Polina; Höfer, Stefanie; Hornisch, Maximilian; Abele, Miriam; Kuster, Bernhard; Médard, Guillaume: Merits of Diazirine Photo-Immobilization for Target Profiling of Natural Products and Cofactors. ACS Chemical Biology, 2022 mehr…
Steimbach, Raphael R.; Herbst-Gervasoni, Corey J.; Lechner, Severin; Stewart, Tracy Murray; Klinke, Glynis; Ridinger, Johannes; Géraldy, Magalie N. E.; Tihanyi, Gergely; Foley, Jackson R.; Uhrig, Ulrike; Kuster, Bernhard; Poschet, Gernot; Casero, Robert A., Jr.; Médard, Guillaume; Oehme, Ina; Christianson, David W.; Gunkel, Nikolas; Miller, Aubry K.: Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. Journal of the American Chemical Society 144 (41), 2022, 18861-18875 mehr…
Stepan, Jens; Heinz, Daniel E.; Dethloff, Frederik; Bajaj, Thomas; Zellner, Andreas; Hafner, Kathrin; Wiechmann, Svenja; Mackert, Sarah; Mecdad, Yara; Rabenstein, Michael; Ebert, Tim; Martinelli, Silvia; Häusl, Alexander S.; Pöhlmann, Maximilian L.; Hermann, Anke; Ma, Xiao; Pavenstädt, Hermann; Schmidt, Mathias V.; Philipsen, Alexandra; Turck, Chris W.; Deussing, Jan M.; Kuster, Bernhard; Wehr, Michael C.; Stein, Valentin; Kremerskothen, Joachim; Wotjak, Carsten T.; Gassen, Nils C.: Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning. Cell Reports 41 (10), 2022, 111766 mehr…
Stumpf, M.; Ecker, V.; Giansanti, P.; Lu, J.; Zenz, T.; Ringshausen, I.; Küster, B.; Ruland, J.; Buchner, M.: P630: TARGETING NEGATIVE REGULATION OF MAPK SIGNALING IN CHRONIC LYMPHOCYTIC LEUKEMIA. HemaSphere 6, 2022, 528-529 mehr…
The, Matthew; Samaras, Patroklos; Kuster, Bernhard; Wilhelm, Mathias: Re-analysis of ProteomicsDB using an accurate, sensitive and scalable false discovery rate estimation approach for protein groups. Molecular & Cellular Proteomics, 2022, 100437 mehr…
Torlot, Lucien; Jarzab, Anna; Albert, Johanna; Pók-Udvari, Ágnes; Stahler, Arndt; Holch, Julian Walter; Gerlinger, Marco; Heinemann, Volker; Klauschen, Frederick; Kirchner, Thomas; Kumbrink, Jörg; Küster, Bernhard; Jung, Andreas: Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance. Journal of Cancer Research and Clinical Oncology 149 (2), 2022, 669-682 mehr…
Weiß, Lukas; Gaelings, Lana; Reiner, Tina; Mergner, Julia; Kuster, Bernhard; Fehér, Attila; Hensel, Götz; Gahrtz, Manfred; Kumlehn, Jochen; Engelhardt, Stefan; Hückelhoven, Ralph: Posttranslational modification of the RHO of plants protein RACB by phosphorylation and cross-kingdom conserved ubiquitination. PLOS ONE 17 (3), 2022, e0258924 mehr…
Zecha, Jana; Gabriel, Wassim; Spallek, Ria; Chang, Yun-Chien; Mergner, Julia; Wilhelm, Mathias; Bassermann, Florian; Kuster, Bernhard: Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling. Nature Communications 13 (1), 2022 mehr…
Zecha, Jana; Gabriel, Wassim; Spallek, Ria; Chang, Yun-Chien; Mergner, Julia; Wilhelm, Mathias; Bassermann, Florian; Kuster, Bernhard: Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling. Nature Communications 13 (1), 2022 mehr…
Zellner, Andreas; Müller, Stephan A.; Lindner, Barbara; Beaufort, Nathalie; Rozemuller, Annemieke J. M.; Arzberger, Thomas; Gassen, Nils C.; Lichtenthaler, Stefan F.; Kuster, Bernhard; Haffner, Christof; Dichgans, Martin: Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates. Acta Neuropathologica Communications 10 (1), 2022 mehr…

2021

Alfaro, Javier Antonio; Bohländer, Peggy; Dai, Mingjie; Filius, Mike; Howard, Cecil J.; van Kooten, Xander F.; Ohayon, Shilo; Pomorski, Adam; Schmid, Sonja; Aksimentiev, Aleksei; Anslyn, Eric V.; Bedran, Georges; Cao, Chan; Chinappi, Mauro; Coyaud, Etienne; Dekker, Cees; Dittmar, Gunnar; Drachman, Nicholas; Eelkema, Rienk; Goodlett, David; Hentz, Sébastien; Kalathiya, Umesh; Kelleher, Neil L.; Kelly, Ryan T.; Kelman, Zvi; Kim, Sung Hyun; Kuster, Bernhard; Rodriguez-Larrea, David; Lindsay, Stuart; Maglia, Giovanni; Marcotte, Edward M.; Marino, John P.; Masselon, Christophe; Mayer, Michael; Samaras, Patroklos; Sarthak, Kumar; Sepiashvili, Lusia; Stein, Derek; Wanunu, Meni; Wilhelm, Mathias; Yin, Peng; Meller, Amit; Joo, Chirlmin: The emerging landscape of single-molecule protein sequencing technologies. Nature Methods 18 (6), 2021, 604-617 mehr…
Baasch, Sebastian; Giansanti, Piero; Kolter, Julia; Riedl, André; Forde, Aaron James; Runge, Solveig; Zenke, Simon; Elling, Roland; Halenius, Anne; Brabletz, Simone; Hengel, Hartmut; Kuster, Bernhard; Brabletz, Thomas; Cicin-Sain, Luka; Arens, Ramon; Vlachos, Andreas; Rohr, Jan Christopher; Stemmler, Marc Philippe; Kopf, Manfred; Ruzsics, Zsolt; Henneke, Philipp: Cytomegalovirus subverts macrophage identity. Cell 184 (14), 2021, 3774-3793.e25 mehr…
Bian, Yangyang; Bayer, Florian P.; Chang, Yun-Chien; Meng, Chen; Hoefer, Stefanie; Deng, Nan; Zheng, Runsheng; Boychenko, Oleksandr; Kuster, Bernhard: Robust Microflow LC-MS/MS for Proteome Analysis: 38 000 Runs and Counting. Analytical Chemistry 93 (8), 2021, 3686-3690 mehr…
Bian, Yangyang; The, Matthew; Giansanti, Piero; Mergner, Julia; Zheng, Runsheng; Wilhelm, Mathias; Boychenko, Alexander; Kuster, Bernhard: Identification of 7 000–9 000 Proteins from Cell Lines and Tissues by Single-Shot Microflow LC–MS/MS. Analytical Chemistry, 2021 mehr…
Breunig, Markus; Merkle, Jessica; Wagner, Martin; Melzer, Michael K.; Barth, Thomas F.E.; Engleitner, Thomas; Krumm, Johannes; Wiedenmann, Sandra; Cohrs, Christian M.; Perkhofer, Lukas; Jain, Gaurav; Krüger, Jana; Hermann, Patrick C.; Schmid, Maximilian; Madácsy, Tamara; Varga, Árpád; Griger, Joscha; Azoitei, Ninel; Müller, Martin; Wessely, Oliver; Robey, Pamela G.; Heller, Sandra; Dantes, Zahra; Reichert, Maximilian; Günes, Cagatay; Bolenz, Christian; Kuhn, Florian; Maléth, József; Speier, Stephan; Liebau, Stefan; Sipos, Bence; Kuster, Bernhard; Seufferlein, Thomas; Rad, Roland; Meier, Matthias; Hohwieler, Meike; Kleger, Alexander: Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells. Cell Stem Cell, 2021 mehr…
Cheung, Tommy K.; Lee, Chien-Yun; Bayer, Florian P.; McCoy, Atticus; Kuster, Bernhard; Rose, Christopher M.: Defining the carrier proteome limit for single-cell proteomics. Nature Methods 18 (1), 2021, 76-83 mehr…
Dieter, Sebastian M.; Siegl, Christine; Codó, Paula L.; Huerta, Mario; Ostermann-Parucha, Anna L.; Schulz, Erik; Zowada, Martina K.; Martin, Sylvia; Laaber, Karin; Nowrouzi, Ali; Blatter, Mona; Kreth, Sina; Westermann, Frank; Benner, Axel; Uhrig, Ulrike; Putzker, Kerstin; Lewis, Joe; Haegebarth, Andrea; Mumberg, Dominik; Holton, Simon J.; Weiske, Joerg; Toepper, Lena-Marit; Scheib, Ulrike; Siemeister, Gerhard; Ball, Claudia R.; Kuster, Bernhard; Stoehr, Gabriele; Hahne, Hannes; Johannes, Sarah; Lange, Martin; Herbst, Friederike; Glimm, Hanno: Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer. Cell Reports 36 (3), 2021, 109394 mehr…
Dölle, Anja; Adhikari, Bikash; Krämer, Andreas; Weckesser, Janik; Berner, Nicola; Berger, Lena-Marie; Diebold, Mathias; Szewczyk, Magdalena M.; Barsyte-Lovejoy, Dalia; Arrowsmith, Cheryl H.; Gebel, Jakob; Löhr, Frank; Dötsch, Volker; Eilers, Martin; Heinzlmeir, Stephanie; Kuster, Bernhard; Sotriffer, Christoph; Wolf, Elmar; Knapp, Stefan: Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. Journal of Medicinal Chemistry 64 (15), 2021, 10682-10710 mehr…
Eckert, Stephan; Chang, Yun-Chien; Bayer, Florian P.; The, Matthew; Kuhn, Peer-Hendrik; Weichert, Wilko; Kuster, Bernhard: Evaluation of Disposable Trap Column nanoLC–FAIMS–MS/MS for the Proteomic Analysis of FFPE Tissue. Journal of Proteome Research 20 (12), 2021, 5402-5411 mehr…
Heider, Michael; Eichner, Ruth; Stroh, Jacob; Morath, Volker; Kuisl, Anna; Zecha, Jana; Lawatscheck, Jannis; Baek, Kheewoong; Garz, Anne-Kathrin; Rudelius, Martina; Deuschle, Friedrich-Christian; Keller, Ulrich; Lemeer, Simone; Verbeek, Mareike; Götze, Katharina S.; Skerra, Arne; Weber, Wolfgang A.; Buchner, Johannes; Schulman, Brenda A.; Kuster, Bernhard; Fernández-Sáiz, Vanesa; Bassermann, Florian: The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma. Molecular Cell 81 (6), 2021, 1170-1186.e10 mehr…
Knecht, Peter; Zhang, Bodong; Reichert, Joachim; Duncan, David A.; Schwarz, Martin; Haag, Felix; Ryan, Paul T. P.; Lee, Tien-Lin; Deimel, Peter S.; Feulner, Peter; Allegretti, Francesco; Auwärter, Willi; Médard, Guillaume; Seitsonen, Ari Paavo; Barth, Johannes V.; Papageorgiou, Anthoula C.: Assembly and Manipulation of a Prototypical N-Heterocyclic Carbene with a Metalloporphyrin Pedestal on a Solid Surface. Journal of the American Chemical Society 143 (11), 2021, 4433-4439 mehr…
Kurz, M; Rieger, L; Giansanti, P; Kuster, B; Bassermann, F: P01.05 Deciphering the function of the ubiquitin-proteasome-system in regulating the immune checkpoint protein B7-H3 (CD276) in non-small cell lung cancer. Poster Presentations, BMJ Publishing Group Ltd, 2021 mehr…
Lageveen‐Kammeijer, Guinevere S. M.; Kuster, Bernhard; Reusch, Dietmar; Wuhrer, Manfred: High sensitivity glycomics in biomedicine. Mass Spectrometry Reviews 41 (6), 2021, 1014-1039 mehr…
Lautenbacher, Ludwig; Samaras, Patroklos; Muller, Julian; Grafberger, Andreas; Shraideh, Marwin; Rank, Johannes; Fuchs, Simon T; Schmidt, Tobias K; The, Matthew; Dallago, Christian; Wittges, Holger; Rost, Burkhard; Krcmar, Helmut; Kuster, Bernhard; Wilhelm, Mathias: ProteomicsDB: toward a FAIR open-source resource for life-science research. Nucleic Acids Research, 2021 mehr…
Martinelli, Silvia; Anderzhanova, Elmira A.; Bajaj, Thomas; Wiechmann, Svenja; Dethloff, Frederik; Weckmann, Katja; Heinz, Daniel E.; Ebert, Tim; Hartmann, Jakob; Geiger, Thomas M.; Döngi, Michael; Hafner, Kathrin; Pöhlmann, Max L.; Jollans, Lee; Philipsen, Alexandra; Schmidt, Susanne V.; Schmidt, Ulrike; Maccarrone, Giuseppina; Stein, Valentin; Hausch, Felix; Turck, Christoph W.; Schmidt, Mathias V.; Gellner, Anne-Kathrin; Kuster, Bernhard; Gassen, Nils C.: Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion. Nature Communications 12 (1), 2021 mehr…
Pal, Jagriti; Becker, Andrea C.; Dhamija, Sonam; Seiler, Jeanette; Abdelkarim, Mahmoud; Sharma, Yogita; Behr, Jürgen; Meng, Chen; Ludwig, Christina; Kuster, Bernhard; Diederichs, Sven: Systematic analysis of migration factors by MigExpress identifies essential cell migration control genes in non‐small cell lung cancer. Molecular Oncology, 2021 mehr…
Philippi, Anne; Heller, Sandra; Costa, Ivan G.; Senée, Valérie; Breunig, Markus; Li, Zhijian; Kwon, Gino; Russell, Ronan; Illing, Anett; Lin, Qiong; Hohwieler, Meike; Degavre, Anne; Zalloua, Pierre; Liebau, Stefan; Schuster, Michael; Krumm, Johannes; Zhang, Xi; Geusz, Ryan; Benthuysen, Jacqueline R.; Wang, Allen; Chiou, Joshua; Gaulton, Kyle; Neubauer, Heike; Simon, Eric; Klein, Thomas; Wagner, Martin; Nair, Gopika; Besse, Céline; Dandine-Roulland, Claire; Olaso, Robert; Deleuze, Jean-François; Kuster, Bernhard; Hebrok, Matthias; Seufferlein, Thomas; Sander, Maike; Boehm, Bernhard O.; Oswald, Franz; Nicolino, Marc; Julier, Cécile; Kleger, Alexander: Mutations and variants of ONECUT1 in diabetes. Nature Medicine, 2021 mehr…
Selkrig, Joel; Stanifer, Megan; Mateus, André; Mitosch, Karin; Barrio‐Hernandez, Inigo; Rettel, Mandy; Kim, Heeyoung; Voogdt, Carlos G P; Walch, Philipp; Kee, Carmon; Kurzawa, Nils; Stein, Frank; Potel, Clément; Jarzab, Anna; Kuster, Bernhard; Bartenschlager, Ralf; Boulant, Steeve; Beltrao, Pedro; Typas, Athanasios; Savitski, Mikhail M: SARS‐CoV‐2 infection remodels the host protein thermal stability landscape. Molecular Systems Biology 17 (2), 2021 mehr…
Stukalov, Alexey; Girault, Virginie; Grass, Vincent; Karayel, Ozge; Bergant, Valter; Urban, Christian; Haas, Darya A.; Huang, Yiqi; Oubraham, Lila; Wang, Anqi; Hamad, M. Sabri; Piras, Antonio; Hansen, Fynn M.; Tanzer, Maria C.; Paron, Igor; Zinzula, Luca; Enghleitner, Thomas; Reinecke, Maria; Lavacca, Teresa M.; Ehmann, Rosina; Wölfel, Roman; Jores, Jörg; Kuster, Bernhard; Protzer, Ulrike; Rad, Roland; Ziebuhr, John; Thiel, Volker; Scaturro, Pietro; Mann, Matthias; Pichlmair, Andreas: Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Nature, 2021 mehr…
Verbruggen, Steven; Gessulat, Siegfried; Gabriels, Ralf; Matsaroki, Anna; Van de Voorde, Hendrik; Kuster, Bernhard; Degroeve, Sven; Martens, Lennart; Van Criekinge, Wim; Wilhelm, Mathias; Menschaert, Gerben: Spectral Prediction Features as a Solution for the Search Space Size Problem in Proteogenomics. Molecular & Cellular Proteomics 20, 2021, 100076 mehr…
Wiechmann, Svenja; Ruprecht, Benjamin; Siekmann, Theresa; Zheng, Runsheng; Frejno, Martin; Kunold, Elena; Bajaj, Thomas; Zolg, Daniel P.; Sieber, Stephan A.; Gassen, Nils C.; Kuster, Bernhard: Chemical Phosphoproteomics Sheds New Light on the Targets and Modes of Action of AKT Inhibitors. ACS Chemical Biology, 2021 mehr…
Wilhelm, Mathias; Zolg, Daniel P.; Graber, Michael; Gessulat, Siegfried; Schmidt, Tobias; Schnatbaum, Karsten; Schwencke-Westphal, Celina; Seifert, Philipp; de Andrade Krätzig, Niklas; Zerweck, Johannes; Knaute, Tobias; Bräunlein, Eva; Samaras, Patroklos; Lautenbacher, Ludwig; Klaeger, Susan; Wenschuh, Holger; Rad, Roland; Delanghe, Bernard; Huhmer, Andreas; Carr, Steven A.; Clauser, Karl R.; Krackhardt, Angela M.; Reimer, Ulf; Kuster, Bernhard: Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics. Nature Communications 12 (1), 2021 mehr…
Zhang, Xiang; Schuhmachers, Patrick; Mourão, André; Giansanti, Piero; Murer, Anita; Thumann, Sybille; Kuklik‐Roos, Cornelia; Beer, Sophie; Hauck, Stefanie M; Hammerschmidt, Wolfgang; Küppers, Ralf; Kuster, Bernhard; Raab, Monika; Strebhardt, Klaus; Sattler, Michael; Münz, Christian; Kempkes, Bettina: PLK1‐dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV‐infected mice. EMBO reports 22 (12), 2021 mehr…

2020

Adhikari, Bikash; Bozilovic, Jelena; Diebold, Mathias; Schwarz, Jessica Denise; Hofstetter, Julia; Schröder, Martin; Wanior, Marek; Narain, Ashwin; Vogt, Markus; Dudvarski Stankovic, Nevenka; Baluapuri, Apoorva; Schönemann, Lars; Eing, Lorenz; Bhandare, Pranjali; Kuster, Bernhard; Schlosser, Andreas; Heinzlmeir, Stephanie; Sotriffer, Christoph; Knapp, Stefan; Wolf, Elmar: PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase. Nature Chemical Biology 16 (11), 2020, 1179-1188 mehr…
Ashwood, Christopher; Bittremieux, Wout; Deutsch, Eric W.; Doncheva, Nadezhda T.; Dorfer, Viktoria; Gabriels, Ralf; Gorshkov, Vladimir; Gupta, Surya; Jones, Andrew R.; Käll, Lukas; Kopczynski, Dominik; Lane, Lydie; Lautenbacher, Ludwig; Legeay, Marc; Locard-Paulet, Marie; Mesuere, Bart; Perez-Riverol, Yasset; Netz, Eugen; Pfeuffer, Julianus; Sachsenberg, Timo; Salz, Renee; Samaras, Patroklos; Schiebenhoefer, Henning; Schmidt, Tobias; Schwämmle, Veit; Soggiu, Alessio; Uszkoreit, Julian; Den Bossche, Tim Van; Van Puyvelde, Bart; Van Strien, Joeri; Verschaffelt, Pieter; Webel, Henry; Willems, Sander: Proceedings of the EuBIC-MS 2020 Developers’ Meeting. EuPA Open Proteomics, 2020 mehr…
Bian, Yangyang; Zheng, Runsheng; Bayer, Florian P.; Wong, Cassandra; Chang, Yun-Chien; Meng, Chen; Zolg, Daniel P.; Reinecke, Maria; Zecha, Jana; Wiechmann, Svenja; Heinzlmeir, Stephanie; Scherr, Johannes; Hemmer, Bernhard; Baynham, Mike; Gingras, Anne-Claude; Boychenko, Oleksandr; Kuster, Bernhard: Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS. Nature Communications 11 (1), 2020 mehr…
Cossa, Giacomo; Roeschert, Isabelle; Prinz, Florian; Baluapuri, Apoorva; Silveira Vidal, Raphael; Schülein-Völk, Christina; Chang, Yun-Chien; Ade, Carsten Patrick; Mastrobuoni, Guido; Girard, Cyrille; Wortmann, Lars; Walz, Susanne; Lührmann, Reinhard; Kempa, Stefan; Kuster, Bernhard; Wolf, Elmar; Mumberg, Dominik; Eilers, Martin: Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription. Molecular Cell 77 (6), 2020, 1322-1339.e11 mehr…
Dietinger, Vanessa; García de Durango, Cira R.; Wiechmann, Svenja; Boos, Sophie L.; Michl, Marlies; Neumann, Jens; Hermeking, Heiko; Kuster, Bernhard; Jung, Peter: Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer. Cell Communication and Signaling 18 (1), 2020 mehr…
Erhart, Friedrich; Hackl, Matthias; Hahne, Hannes; Buchroithner, Johanna; Meng, Chen; Klingenbrunner, Simone; Reitermaier, René; Fischhuber, Katrin; Skalicky, Susanna; Berger, Walter; Spiegl-Kreinecker, Sabine; Lötsch, Daniela; Ricken, Gerda; Kuster, Bernhard; Wöhrer, Adelheid; Widhalm, Georg; Hainfellner, Johannes; Felzmann, Thomas; Dohnal, Alexander M.; Marosi, Christine; Visus, Carmen: Combined proteomics/miRNomics of dendritic cell immunotherapy-treated glioblastoma patients as a screening for survival-associated factors. npj Vaccines 5 (1), 2020 mehr…
Flosbach, Markus; Oberle, Susanne G.; Scherer, Stefanie; Zecha, Jana; von Hoesslin, Madlaina; Wiede, Florian; Chennupati, Vijaykumar; Cullen, Jolie G.; List, Markus; Pauling, Josch K.; Baumbach, Jan; Kuster, Bernhard; Tiganis, Tony; Zehn, Dietmar: PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells. Cell Reports 32 (4), 2020, 107957 mehr…
Frejno, Martin; Meng, Chen; Ruprecht, Benjamin; Oellerich, Thomas; Scheich, Sebastian; Kleigrewe, Karin; Drecoll, Enken; Samaras, Patroklos; Hogrebe, Alexander; Helm, Dominic; Mergner, Julia; Zecha, Jana; Heinzlmeir, Stephanie; Wilhelm, Mathias; Dorn, Julia; Kvasnicka, Hans-Michael; Serve, Hubert; Weichert, Wilko; Kuster, Bernhard: Proteome activity landscapes of tumor cell lines determine drug responses. Nature Communications 11 (1), 2020 mehr…
Hoermann, Bernhard; Kokot, Thomas; Helm, Dominic; Heinzlmeir, Stephanie; Chojnacki, Jeremy E.; Schubert, Thomas; Ludwig, Christina; Berteotti, Anna; Kurzawa, Nils; Kuster, Bernhard; Savitski, Mikhail M.; Köhn, Maja: Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A. Nature Communications 11 (1), 2020 mehr…
Jarzab, Anna; Kurzawa, Nils; Hopf, Thomas; Moerch, Matthias; Zecha, Jana; Leijten, Niels; Bian, Yangyang; Musiol, Eva; Maschberger, Melanie; Stoehr, Gabriele; Becher, Isabelle; Daly, Charlotte; Samaras, Patroklos; Mergner, Julia; Spanier, Britta; Angelov, Angel; Werner, Thilo; Bantscheff, Marcus; Wilhelm, Mathias; Klingenspor, Martin; Lemeer, Simone; Liebl, Wolfgang; Hahne, Hannes; Savitski, Mikhail M.; Kuster, Bernhard: Meltome atlas—thermal proteome stability across the tree of life. Nature Methods 17 (5), 2020, 495-503 mehr…
Kreutmair, Stefanie; Erlacher, Miriam; Andrieux, Geoffroy; Istvanffy, Rouzanna; Mueller-Rudorf, Alina; Zwick, Melissa; Rückert, Tamina; Pantic, Milena; Poggio, Teresa; Shoumariyeh, Khalid; Mueller, Tony A.; Kawaguchi, Hiroyuki; Follo, Marie; Klingeberg, Cathrin; Wlodarski, Marcin; Baumann, Irith; Pfeifer, Dietmar; Kulinski, Michal; Rudelius, Martina; Lemeer, Simone; Kuster, Bernhard; Dierks, Christine; Peschel, Christian; Cabezas-Wallscheid, Nina; Duque-Afonso, Jesus; Zeiser, Robert; Cleary, Michael L.; Schindler, Detlev; Schmitt-Graeff, Annette; Boerries, Melanie; Niemeyer, Charlotte M.; Oostendorp, Robert A.J.; Duyster, Justus; Illert, Anna Lena: Loss of the Fanconi anemia–associated protein NIPA causes bone marrow failure. Journal of Clinical Investigation 130 (6), 2020, 2827-2844 mehr…
Lampl, Sandra; Janas, Marianne K.; Donakonda, Sainitin; Brugger, Marcus; Lohr, Kerstin; Schneider, Annika; Manske, Katrin; Sperl, Laura E.; Kläger, Susan; Küster, Bernhard; Wettmarshausen, Jennifer; Müller, Constanze; Laschinger, Melanie; Hartmann, Daniel; Hüser, Norber; Perocchi, Fabiana; Schmitt-Kopplin, Philippe; Hagn, Franz; Zender, Lars; Hornung, Veit; Borner, Christoph; Pichlmair, Andreas; Kashkar, Hamid; Klingenspor, Martin; Prinz, Marco; Schreiner, Sabrina; Conrad, Marcus; Jost, Philipp J.; Zischka, Hans; Steiger, Katja; Krönke, Martin; Zehn, Dietmar; Protzer, Ulrike; Heikenwälder, Mathias; Knolle, Percy A.; Wohlleber, Dirk: Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes. Journal of Hepatology 73 (6), 2020, 1347-1359 mehr…
Li, Hui; Mercer, Ryan; Behr, Jürgen; Heinzlmeir, Stephanie; McMullen, Lynn M.; Vogel, Rudi F.; Gänzle, Michael G.: Heat and Pressure Resistance in Escherichia coli Relates to Protein Folding and Aggregation. Frontiers in Microbiology 11, 2020 mehr…
Mergner, Julia; Frejno, Martin; List, Markus; Papacek, Michael; Chen, Xia; Chaudhary, Ajeet; Samaras, Patroklos; Richter, Sandra; Shikata, Hiromasa; Messerer, Maxim; Lang, Daniel; Altmann, Stefan; Cyprys, Philipp; Zolg, Daniel P.; Mathieson, Toby; Bantscheff, Marcus; Hazarika, Rashmi R.; Schmidt, Tobias; Dawid, Corinna; Dunkel, Andreas; Hofmann, Thomas; Sprunck, Stefanie; Falter-Braun, Pascal; Johannes, Frank; Mayer, Klaus F. X.; Jürgens, Gerd; Wilhelm, Mathias; Baumbach, Jan; Grill, Erwin; Schneitz, Kay; Schwechheimer, Claus; Kuster, Bernhard: Mass-spectrometry-based draft of the Arabidopsis proteome. Nature 579 (7799), 2020, 409-414 mehr…
Mergner, Julia; Frejno, Martin; Messerer, Maxim; Lang, Daniel; Samaras, Patroklos; Wilhelm, Mathias; Mayer, Klaus F. X.; Schwechheimer, Claus; Kuster, Bernhard: Proteomic and transcriptomic profiling of aerial organ development in Arabidopsis. Scientific Data 7 (1), 2020 mehr…
Montenegro, Raquel Carvalho; Howarth, Alison; Ceroni, Alessandro; Fedele, Vita; Farran, Batoul; Mesquita, Felipe Pantoja; Frejno, Martin; Berger, Benedict-Tilman; Heinzlmeir, Stephanie; Sailem, Heba Z.; Tesch, Roberta; Ebner, Daniel; Knapp, Stefan; Burbano, Rommel; Kuster, Bernhard; Müller, Susanne: Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib. Oncotarget 11 (5), 2020, 535-549 mehr…
Schöttl, Theresa; Pachl, Fiona; Giesbertz, Pieter; Daniel, Hannelore; Kuster, Bernhard; Fromme, Tobias; Klingenspor, Martin: Proteomic and Metabolite Profiling Reveals Profound Structural and Metabolic Reorganization of Adipocyte Mitochondria in Obesity. Obesity 28 (3), 2020, 590-600 mehr…
Searle, Brian C.; Swearingen, Kristian E.; Barnes, Christopher A.; Schmidt, Tobias; Gessulat, Siegfried; Küster, Bernhard; Wilhelm, Mathias: Generating high quality libraries for DIA MS with empirically corrected peptide predictions. Nature Communications 11 (1), 2020 mehr…
Sellmer, Andreas; Pilsl, Bernadette; Beyer, Mandy; Pongratz, Herwig; Wirth, Lukas; Elz, Sigurd; Dove, Stefan; Henninger, Sven Julian; Spiekermann, Karsten; Polzer, Harald; Klaeger, Susan; Kuster, Bernhard; Böhmer, Frank D.; Fiebig, Heinz-Herbert; Krämer, Oliver H.; Mahboobi, Siavosh: A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia. European Journal of Medicinal Chemistry 193, 2020, 112232 mehr…
Wiechmann, Svenja; Saupp, Elena; Schilling, Daniela; Heinzlmeir, Stephanie; Schneider, Günter; Schmid, Roland M.; Combs, Stephanie E.; Kuster, Bernhard; Dobiasch, Sophie: Radiosensitization by kinase inhibition revealed by phosphoproteomic analysis of pancreatic cancer cells. Molecular & Cellular Proteomics, 2020, mcp.RA120.002046 mehr…
Zecha, Jana; Lee, Chien-Yun; Bayer, Florian P.; Meng, Chen; Grass, Vincent; Zerweck, Johannes; Schnatbaum, Karsten; Michler, Thomas; Pichlmair, Andreas; Ludwig, Christina; Kuster, Bernhard: Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing. Molecular & Cellular Proteomics 19 (9), 2020, 1503-1522 mehr…

2019

Djukovic, Ana; González-Barberá, Eva M.; Sanz, Jaime; Artacho, Alejandro; Peñaranda, Iván; Herrera, Beatriz; Garzón, María José; Salavert, Miguel; López-Hontangas, José Luis; Xavier, Karina B.; Kuster, Bernhard; Debrauwer, Laurent; Rolain, Jean-Marc; Sanz, Miguel A.; Xavier, Joao B.; Ubeda, Carles: High Heterogeneity of Multidrug-Resistant Enterobacteriaceae Fecal Levels in Hospitalized Patients Is Partially Driven by Intravenous β-Lactams. Antimicrobial Agents and Chemotherapy 64 (2), 2019 mehr…
Eraslan, Basak; Wang, Dongxue; Gusic, Mirjana; Prokisch, Holger; Hallström, Björn M; Uhlén, Mathias; Asplund, Anna; Pontén, Frederik; Wieland, Thomas; Hopf, Thomas; Hahne, Hannes; Kuster, Bernhard; Gagneur, Julien: Quantification and discovery of sequence determinants of protein‐per‐mRNA amount in 29 human tissues. Molecular Systems Biology 15 (2), 2019 mehr…
Gessulat, Siegfried; Schmidt, Tobias; Zolg, Daniel Paul; Samaras, Patroklos; Schnatbaum, Karsten; Zerweck, Johannes; Knaute, Tobias; Rechenberger, Julia; Delanghe, Bernard; Huhmer, Andreas; Reimer, Ulf; Ehrlich, Hans-Christian; Aiche, Stephan; Kuster, Bernhard; Wilhelm, Mathias: Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning. Nature Methods 16 (6), 2019, 509-518 mehr…
Jing, Chao; Zhang, Bodong; Synkule, Sabine; Ebrahimi, Maryam; Riss, Alexander; Auwärter, Willi; Jiang, Li; Médard, Guillaume; Reichert, Joachim; Barth, Johannes V.; Papageorgiou, Anthoula C.: Snapshots of Dynamic Adaptation: Two‐Dimensional Molecular Architectonics with Linear Bis‐Hydroxamic Acid Modules. Angewandte Chemie International Edition 58 (52), 2019, 18948-18956 mehr…
Kalde, Monika; Elliott, Liam; Ravikumar, Raksha; Rybak, Katarzyna; Altmann, Melina; Klaeger, Susan; Wiese, Christian; Abele, Miriam; Al, Benjamin; Kalbfuß, Nils; Qi, Xingyun; Steiner, Alexander; Meng, Chen; Zheng, Huanquan; Kuster, Bernhard; Falter‐Braun, Pascal; Ludwig, Christina; Moore, Ian; Assaad, Farhah F.: Interactions between Transport Protein Particle (TRAPP) complexes and Rab GTP ases in Arabidopsis. The Plant Journal 100 (2), 2019, 279-297 mehr…
Khakipoor, Shokoufeh; Giannaki, Marina; Theparambil, Shefeeq M.; Zecha, Jana; Küster, Bernhard; Heermann, Stephan; Deitmer, Joachim W.; Roussa, Eleni: Functional expression of electrogenic sodium bicarbonate cotransporter 1 (NBCe1) in mouse cortical astrocytes is dependent on S255‐257 and regulated by mTOR. Glia 67 (12), 2019, 2264-2278 mehr…
Lalaoui, Rym; Djukovic, Ana; Bakour, Sofiane; Sanz, Jaime; Gonzalez-Barbera, Eva M.; Salavert, Miguel; López-Hontangas, Jose Luis; Sanz, Miguel A.; Xavier, Karina B.; Kuster, Bernhard; Debrauwer, Laurent; Ubeda, Carles; Rolain, Jean-Marc: Detection of plasmid-mediated colistin resistance, mcr-1 gene, in Escherichia coli isolated from high-risk patients with acute leukemia in Spain. Journal of Infection and Chemotherapy 25 (8), 2019, 605-609 mehr…
Le, Philipp; Kunold, Elena; Macsics, Robert; Rox, Katharina; Jennings, Megan C.; Ugur, Ilke; Reinecke, Maria; Chaves-Moreno, Diego; Hackl, Mathias W.; Fetzer, Christian; Mandl, Franziska A. M.; Lehmann, Johannes; Korotkov, Vadim S.; Hacker, Stephan M.; Kuster, Bernhard; Antes, Iris; Pieper, Dietmar H.; Rohde, Manfred; Wuest, William M.; Medina, Eva; Sieber, Stephan A.: Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms. Nature Chemistry 12 (2), 2019, 145-158 mehr…
Meng, Chen; Basunia, Azfar; Peters, Bjoern; Gholami, Amin Moghaddas; Kuster, Bernhard; Culhane, Aedín C.: MOGSA: Integrative Single Sample Gene-set Analysis of Multiple Omics Data. Molecular & Cellular Proteomics 18 (8 suppl 1), 2019, S153-S168 mehr…
Mucha, Stefanie; Heinzlmeir, Stephanie; Kriechbaumer, Verena; Strickland, Benjamin; Kirchhelle, Charlotte; Choudhary, Manisha; Kowalski, Natalie; Eichmann, Ruth; Hueckelhoven, Ralph; Grill, Erwin; Kuster, Bernhard; Glawischnig, Erich: The formation of a camalexin-biosynthetic metabolon. The Plant Cell, 2019, tpc.00403.2019 mehr…
Rechenberger, Julia; Samaras, Patroklos; Jarzab, Anna; Behr, Juergen; Frejno, Martin; Djukovic, Ana; Sanz, Jaime; González-Barberá, Eva M.; Salavert, Miguel; López-Hontangas, Jose Luis; Xavier, Karina B.; Debrauwer, Laurent; Rolain, Jean-Marc; Sanz, Miguel; Garcia-Garcera, Marc; Wilhelm, Mathias; Ubeda, Carles; Kuster, Bernhard: Challenges in Clinical Metaproteomics Highlighted by the Analysis of Acute Leukemia Patients with Gut Colonization by Multidrug-Resistant Enterobacteriaceae. Proteomes 7 (1), 2019, 2 mehr…
Reinecke, Maria; Heinzlmeir, Stephanie; Wilhelm, Mathias; Médard, Guillaume; Klaeger, Susan; Kuster, Bernhard: Kinobeads: A Chemical Proteomic Approach for Kinase Inhibitor Selectivity Profiling and Target Discovery. Target Discovery and Validation: Methods and Strategies for Drug Discovery, 2019, 97--130 mehr…
Reinecke, Maria; Ruprecht, Benjamin; Poser, Sandra; Wiechmann, Svenja; Wilhelm, Mathias; Heinzlmeir, Stephanie; Kuster, Bernhard; Médard, Guillaume: Chemoproteomic Selectivity Profiling of PIKK and PI3K Kinase Inhibitors. ACS Chemical Biology 14 (4), 2019, 655-664 mehr…
Ruschhaupt, Moritz; Mergner, Julia; Mucha, Stefanie; Papacek, Michael; Doch, Isabel; Tischer, Stefanie V; Hemmler, Daniel; Chiasson, David; Edel, Kai H; Kudla, Jörg; Schmitt‐Kopplin, Philippe; Kuster, Bernhard; Grill, Erwin: Rebuilding core abscisic acid signaling pathways of Arabidopsis in yeast. The EMBO Journal 38 (17), 2019 mehr…
Samaras, Patroklos; Schmidt, Tobias; Frejno, Martin; Gessulat, Siegfried; Reinecke, Maria; Jarzab, Anna; Zecha, Jana; Mergner, Julia; Giansanti, Piero; Ehrlich, Hans-Christian; Aiche, Stephan; Rank, Johannes; Kienegger, Harald; Krcmar, Helmut; Kuster, Bernhard; Wilhelm, Mathias: ProteomicsDB: a multi-omics and multi-organism resource for life science research. Nucleic Acids Research, 2019 mehr…
Schirle, Markus; Bantscheff, Marcus; Kuster, Bernhard: Characterization of Drug-Protein Interactions by Chemoproteomics. In: Proteomics for Biological Discovery. John Wiley & Sons, Inc., 2019 mehr…
Seefried, Florian; Schmidt, Tobias; Reinecke, Maria; Heinzlmeir, Stephanie; Kuster, Bernhard; Wilhelm, Mathias: CiRCus: A Framework to Enable Classification of Complex High-Throughput Experiments. Journal of Proteome Research 18 (4), 2019, 1486-1493 mehr…
Verbruggen, Steven; Ndah, Elvis; Van Criekinge, Wim; Gessulat, Siegfried; Kuster, Bernhard; Wilhelm, Mathias; Van Damme, Petra; Menschaert, Gerben: PROTEOFORMER 2.0: Further Developments in the Ribosome Profiling-assisted Proteogenomic Hunt for New Proteoforms. Molecular & Cellular Proteomics 18 (8 suppl 1), 2019, S126-S140 mehr…
Wang, Dongxue; Eraslan, Basak; Wieland, Thomas; Hallström, Björn; Hopf, Thomas; Zolg, Daniel Paul; Zecha, Jana; Asplund, Anna; Li, Li‐hua; Meng, Chen; Frejno, Martin; Schmidt, Tobias; Schnatbaum, Karsten; Wilhelm, Mathias; Ponten, Frederik; Uhlen, Mathias; Gagneur, Julien; Hahne, Hannes; Kuster, Bernhard: A deep proteome and transcriptome abundance atlas of 29 healthy human tissues. Molecular Systems Biology 15 (2), 2019 mehr…
Zecha, Jana; Satpathy, Shankha; Kanashova, Tamara; Avanessian, Shayan C.; Kane, M. Harry; Clauser, Karl R.; Mertins, Philipp; Carr, Steven A.; Kuster, Bernhard: TMT Labeling for the Masses: A Robust and Cost-efficient, In-solution Labeling Approach. Molecular & Cellular Proteomics 18 (7), 2019, 1468-1478 mehr…
Zhang, Bing; Kuster, Bernhard: Proteomics Is Not an Island: Multi-omics Integration Is the Key to Understanding Biological Systems. Molecular & Cellular Proteomics 18 (8 suppl 1), 2019, S1-S4 mehr…

2018

Bader, Matthias; Dunkel, Andreas; Wenning, Mareike; Kohler, Bernd; Medard, Guillaume; del Castillo, Estela; Gholami, Amin; Kuster, Bernhard; Scherer, Siegfried; Hofmann, Thomas: Dynamic Proteome Alteration and Functional Modulation of Human Saliva Induced by Dietary Chemosensory Stimuli. Journal of Agricultural and Food Chemistry 66 (22), 2018, 5621-5634 mehr…
Buhner, Sabine; Hahne, Hannes; Hartwig, Kerstin; Li, Qin; Vignali, Sheila; Ostertag, Daniela; Meng, Chen; Hörmannsperger, Gabriele; Braak, Breg; Pehl, Christian; Frieling, Thomas; Barbara, Giovanni; De Giorgio, Roberto; Demir, Ihsan Ekin; Ceyhan, Güralp Onur; Zeller, Florian; Boeckxstaens, Guy; Haller, Dirk; Kuster, Bernhard; Schemann, Michael: Protease signaling through protease activated receptor 1 mediate nerve activation by mucosal supernatants from irritable bowel syndrome but not from ulcerative colitis patients. PLOS ONE 13 (3), 2018, e0193943 mehr…
Deutsch, Eric W.; Perez-Riverol, Yasset; Chalkley, Robert J.; Wilhelm, Mathias; Tate, Stephen; Sachsenberg, Timo; Walzer, Mathias; Käll, Lukas; Delanghe, Bernard; Böcker, Sebastian; Schymanski, Emma L.; Wilmes, Paul; Dorfer, Viktoria; Kuster, Bernhard; Volders, Pieter-Jan; Jehmlich, Nico; Vissers, Johannes P. C.; Wolan, Dennis W.; Wang, Ana Y.; Mendoza, Luis; Shofstahl, Jim; Dowsey, Andrew W.; Griss, Johannes; Salek, Reza M.; Neumann, Steffen; Binz, Pierre-Alain; Lam, Henry; Vizcaíno, Juan Antonio; Bandeira, Nuno; Röst, Hannes: Expanding the Use of Spectral Libraries in Proteomics. Journal of Proteome Research 17 (12), 2018, 4051-4060 mehr…
Heinze, Simon; Zimmermann, Kerstin; Ludwig, Christina; Heinzlmeir, Stephanie; Schwarz, Wolfgang H.; Zverlov, Vladimir V.; Liebl, Wolfgang; Kornberger, Petra: Evaluation of promoter sequences for the secretory production of a Clostridium thermocellum cellulase in Paenibacillus polymyxa. Applied Microbiology and Biotechnology 102 (23), 2018, 10147-10159 mehr…
Kindt, Alida; Liebisch, Gerhard; Clavel, Thomas; Haller, Dirk; Hörmannsperger, Gabriele; Yoon, Hongsup; Kolmeder, Daniela; Sigruener, Alexander; Krautbauer, Sabrina; Seeliger, Claudine; Ganzha, Alexandra; Schweizer, Sabine; Morisset, Rosalie; Strowig, Till; Daniel, Hannelore; Helm, Dominic; Küster, Bernhard; Krumsiek, Jan; Ecker, Josef: The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice. Nature Communications 9 (1), 2018 mehr…
Lassabe, Gabriel; Kramer, Karl; Hammock, Bruce D.; González-Sapienza, Gualberto; González-Techera, Andrés: Noncompetitive Homogeneous Detection of Small Molecules Using Synthetic Nanopeptamer-Based Luminescent Oxygen Channeling. Analytical Chemistry 90 (10), 2018, 6187-6192 mehr…
Lee, Chien-Yun; Wang, Dongxue; Wilhelm, Mathias; Zolg, Daniel P.; Schmidt, Tobias; Schnatbaum, Karsten; Reimer, Ulf; Pontén, Fredrik; Uhlén, Mathias; Hahne, Hannes; Kuster, Bernhard: Mining the Human Tissue Proteome for Protein Citrullination. Molecular & Cellular Proteomics 17 (7), 2018, 1378-1391 mehr…
Mathew, Nimitha R; Baumgartner, Francis; Braun, Lukas; O'Sullivan, David; Thomas, Simone; Waterhouse, Miguel; Müller, Tony A; Hanke, Kathrin; Taromi, Sanaz; Apostolova, Petya; Illert, Anna L; Melchinger, Wolfgang; Duquesne, Sandra; Schmitt-Graeff, Annette; Osswald, Lena; Yan, Kai-Li; Weber, Arnim; Tugues, Sonia; Spath, Sabine; Pfeifer, Dietmar; Follo, Marie; Claus, Rainer; Lübbert, Michael; Rummelt, Christoph; Bertz, Hartmut; Wäsch, Ralph; Haag, Johanna; Schmidts, Andrea; Schultheiss, Michael; Bettinger, Dominik; Thimme, Robert; Ullrich, Evelyn; Tanriver, Yakup; Vuong, Giang Lam; Arnold, Renate; Hemmati, Philipp; Wolf, Dominik; Ditschkowski, Markus; Jilg, Cordula; Wilhelm, Konrad; Leiber, Christian; Gerull, Sabine; Halter, Jörg; Lengerke, Claudia; Pabst, Thomas; Schroeder, Thomas; Kobbe, Guido; Rösler, Wolf; Doostkam, Soroush; Meckel, Stephan et al.: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature Medicine 24 (3), 2018, 282-291 mehr…
Mathew, Nimitha R; Baumgartner, Francis; Braun, Lukas; O'Sullivan, David; Thomas, Simone; Waterhouse, Miguel; Müller, Tony A; Hanke, Kathrin; Taromi, Sanaz; Apostolova, Petya; Illert, Anna L; Melchinger, Wolfgang; Duquesne, Sandra; Schmitt-Graeff, Annette; Osswald, Lena; Yan, Kai-Li; Weber, Arnim; Tugues, Sonia; Spath, Sabine; Pfeifer, Dietmar; Follo, Marie; Claus, Rainer; Lübbert, Michael; Rummelt, Christoph; Bertz, Hartmut; Wäsch, Ralph; Haag, Johanna; Schmidts, Andrea; Schultheiss, Michael; Bettinger, Dominik; Thimme, Robert; Ullrich, Evelyn; Tanriver, Yakup; Vuong, Giang Lam; Arnold, Renate; Hemmati, Philipp; Wolf, Dominik; Ditschkowski, Markus; Jilg, Cordula; Wilhelm, Konrad; Leiber, Christian; Gerull, Sabine; Halter, Jörg; Lengerke, Claudia; Pabst, Thomas; Schroeder, Thomas; Kobbe, Guido; Rösler, Wolf; Doostkam, Soroush; Meckel, Stephan et al.: Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature Medicine 24 (4), 2018, 526--526 mehr…
Mulder, Celine; Prust, Nadine; van Doorn, Sander; Reinecke, Maria; Kuster, Bernhard; van Bergen en Henegouwen, Paul; Lemeer, Simone: Adaptive Resistance to EGFR-Targeted Therapy by Calcium Signaling in NSCLC Cells. Molecular Cancer Research 16 (11), 2018, 1773-1784 mehr…
Médard, Guillaume; Papageorgiou, Anthoula C.: Surface anchors target golden bullets. Nature Chemistry 11 (1), 2018, 20-22 mehr…
Prechtl, Roman M.; Janßen, Dorothee; Behr, Jürgen; Ludwig, Christina; Küster, Bernhard; Vogel, Rudi F.; Jakob, Frank: Sucrose-Induced Proteomic Response and Carbohydrate Utilization of Lactobacillus sakei TMW 1.411 During Dextran Formation. Frontiers in Microbiology 9, 2018 mehr…
Roehrer, Simon; Behr, Juergen; Stork, Verena; Ramires, Mara; Médard, Guillaume; Frank, Oliver; Kleigrewe, Karin; Hofmann, Thomas; Minceva, Mirjana: Xanthohumol C, a minor bioactive hop compound: Production, purification strategies and antimicrobial test. Journal of Chromatography B 1095, 2018, 39-49 mehr…
Tröster, Alix; Heinzlmeir, Stephanie; Berger, Benedict-Tilman; Gande, Santosh L.; Saxena, Krishna; Sreeramulu, Sridhar; Linhard, Verena; Nasiri, Amir H.; Bolte, Michael; Müller, Susanne; Kuster, Bernhard; Médard, Guillaume; Kudlinzki, Denis; Schwalbe, Harald: NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family. ChemMedChem 13 (16), 2018, 1629-1633 mehr…
Yoon, Hongsup; Schaubeck, Monika; Lagkouvardos, Ilias; Blesl, Andreas; Heinzlmeir, Stephanie; Hahne, Hannes; Clavel, Thomas; Panda, Suchita; Ludwig, Christina; Kuster, Bernhard; Manichanh, Chaysavanh; Kump, Patrizia; Haller, Dirk; Hörmannsperger, Gabriele: Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers Colitis. Cellular and Molecular Gastroenterology and Hepatology 6 (3), 2018, 370-388.e3 mehr…
Zecha, Jana; Meng, Chen; Zolg, Daniel Paul; Samaras, Patroklos; Wilhelm, Mathias; Kuster, Bernhard: Peptide Level Turnover Measurements Enable the Study of Proteoform Dynamics. Molecular & Cellular Proteomics 17 (5), 2018, 974-992 mehr…
Zolg, Daniel Paul; Wilhelm, Mathias; Schmidt, Tobias; Médard, Guillaume; Zerweck, Johannes; Knaute, Tobias; Wenschuh, Holger; Reimer, Ulf; Schnatbaum, Karsten; Kuster, Bernhard: ProteomeTools: Systematic Characterization of 21 Post-translational Protein Modifications by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Using Synthetic Peptides. Molecular & Cellular Proteomics 17 (9), 2018, 1850-1863 mehr…

2017

Arduino, Daniela M.; Wettmarshausen, Jennifer; Vais, Horia; Navas-Navarro, Paloma; Cheng, Yiming; Leimpek, Anja; Ma, Zhongming; Delrio-Lorenzo, Alba; Giordano, Andrea; Garcia-Perez, Cecilia; Médard, Guillaume; Kuster, Bernhard; García-Sancho, Javier; Mokranjac, Dejana; Foskett, J. Kevin; Alonso, M. Teresa; Perocchi, Fabiana: Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening. Molecular Cell 67 (4), 2017, 711-723.e7 mehr…
Delius, Judith; Médard, Guillaume; Kuster, Bernhard; Hofmann, Thomas: Effect of Astringent Stimuli on Salivary Protein Interactions Elucidated by Complementary Proteomics Approaches. Journal of Agricultural and Food Chemistry 65 (10), 2017, 2147-2154 mehr…
Delius, Judith; Trautmann, Simone; Médard, Guillaume; Kuster, Bernhard; Hannig, Matthias; Hofmann, Thomas: Label-free quantitative proteome analysis of the surface-bound salivary pellicle. Colloids and Surfaces B: Biointerfaces 152, 2017, 68-76 mehr…
Feil, Gerhard; Horres, Ralf; Schulte, Julia; Mack, Andreas F.; Petzoldt, Svenja; Arnold, Caroline; Meng, Chen; Jost, Lukas; Boxleitner, Jochen; Kiessling-Wolf, Nicole; Serbest, Ender; Helm, Dominic; Kuster, Bernhard; Hartmann, Isabel; Korff, Thomas; Hahne, Hannes: Bacterial Cellulose Shifts Transcriptome and Proteome of Cultured Endothelial Cells Towards Native Differentiation. Molecular & Cellular Proteomics 16 (9), 2017, 1563-1577 mehr…
Frejno, Martin; Zenezini Chiozzi, Riccardo; Wilhelm, Mathias; Koch, Heiner; Zheng, Runsheng; Klaeger, Susan; Ruprecht, Benjamin; Meng, Chen; Kramer, Karl; Jarzab, Anna; Heinzlmeir, Stephanie; Johnstone, Elaine; Domingo, Enric; Kerr, David; Jesinghaus, Moritz; Slotta‐Huspenina, Julia; Weichert, Wilko; Knapp, Stefan; Feller, Stephan M; Kuster, Bernhard: Pharmacoproteomic characterisation of human colon and rectal cancer. Molecular Systems Biology 13 (11), 2017, 951 mehr…
Heinzlmeir, Stephanie; Lohse, Jonas; Treiber, Tobias; Kudlinzki, Denis; Linhard, Verena; Gande, Santosh Lakshmi; Sreeramulu, Sridhar; Saxena, Krishna; Liu, Xiaofeng; Wilhelm, Mathias; Schwalbe, Harald; Kuster, Bernhard; Médard, Guillaume: Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors. ChemMedChem 12 (12), 2017, 999-1011 mehr…
Hillreiner, Maria; Müller, Nadine I.; Koch, Heiner M.; Schmautz, Christiane; Küster, Bernhard; Pfaffl, Michael W.; Kliem, Heike: Establishment of a 3D cell culture model of primary bovine mammary epithelial cells extracted from fresh milk. In Vitro Cellular & Developmental Biology - Animal 53 (8), 2017, 706-720 mehr…
Hinz, Laura; Ahles, Andrea; Ruprecht, Benjamin; Küster, Bernhard; Engelhardt, Stefan: Two serines in the distal C-terminus of the human ß1-adrenoceptor determine ß-arrestin2 recruitment. PLOS ONE 12 (5), 2017, e0176450 mehr…
Jiang, Li; Zhang, Bodong; Médard, Guillaume; Seitsonen, Ari Paavo; Haag, Felix; Allegretti, Francesco; Reichert, Joachim; Kuster, Bernhard; Barth, Johannes V.; Papageorgiou, Anthoula C.: N-Heterocyclic carbenes on close-packed coinage metal surfaces: bis-carbene metal adatom bonding scheme of monolayer films on Au, Ag and Cu. Chemical Science 8 (12), 2017, 8301-8308 mehr…
Klaeger, Susan; Heinzlmeir, Stephanie; Wilhelm, Mathias; Polzer, Harald; Vick, Binje; Koenig, Paul-Albert; Reinecke, Maria; Ruprecht, Benjamin; Petzoldt, Svenja; Meng, Chen; Zecha, Jana; Reiter, Katrin; Qiao, Huichao; Helm, Dominic; Koch, Heiner; Schoof, Melanie; Canevari, Giulia; Casale, Elena; Depaolini, Stefania Re; Feuchtinger, Annette; Wu, Zhixiang; Schmidt, Tobias; Rueckert, Lars; Becker, Wilhelm; Huenges, Jan; Garz, Anne-Kathrin; Gohlke, Bjoern-Oliver; Zolg, Daniel Paul; Kayser, Gian; Vooder, Tonu; Preissner, Robert; Hahne, Hannes; Tõnisson, Neeme; Kramer, Karl; Götze, Katharina; Bassermann, Florian; Schlegl, Judith; Ehrlich, Hans-Christian; Aiche, Stephan; Walch, Axel; Greif, Philipp A.; Schneider, Sabine; Felder, Eduard Rudolf; Ruland, Juergen; Médard, Guillaume; Jeremias, Irmela; Spiekermann, Karsten; Kuster, Bernhard: The target landscape of clinical kinase drugs. Science 358 (6367), 2017, eaan4368 mehr…
Lohse, Jonas; Schindl, Alexandra; Danda, Natasha; Williams, Chris P.; Kramer, Karl; Kuster, Bernhard; Witte, Martin D.; Médard, Guillaume: Target and identify: triazene linker helps identify azidation sites of labelled proteins via click and cleave strategy. Chem. Commun. 53 (87), 2017, 11929-11932 mehr…
Lohse, Jonas; Swier, Lotteke J.Y.M.; Oudshoorn, Ruben C.; Médard, Guillaume; Kuster, Bernhard; Slotboom, Dirk-Jan; Witte, Martin D.: Targeted Diazotransfer Reagents Enable Selective Modification of Proteins with Azides. Bioconjugate Chemistry 28 (4), 2017, 913-917 mehr…
Marx, Harald; Hahne, Hannes; Ulbrich, Susanne E.; Schnieke, Angelika; Rottmann, Oswald; Frishman, Dmitrij; Kuster, Bernhard: Annotation of the Domestic Pig Genome by Quantitative Proteogenomics. Journal of Proteome Research 16 (8), 2017, 2887-2898 mehr…
Mergner, Julia; Kuster, Bernhard; Schwechheimer, Claus: DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis inArabidopsis. Journal of Biological Chemistry 292 (9), 2017, 3854-3865 mehr…
Moser, Christina; Rüdiger, Daniel; Förster, Florian; von Blume, Julia; Yu, Peng; Kuster, Bernhard; Kazmaier, Uli; Vollmar, Angelika M.; Zahler, Stefan: Persistent inhibition of pore-based cell migration by sub-toxic doses of miuraenamide, an actin filament stabilizer. Scientific Reports 7 (1), 2017 mehr…
Nagel, Marie-Kristin; Kalinowska, Kamila; Vogel, Karin; Reynolds, Gregory D.; Wu, Zhixiang; Anzenberger, Franziska; Ichikawa, Mie; Tsutsumi, Chie; Sato, Masa H.; Kuster, Bernhard; Bednarek, Sebastian Y.; Isono, Erika: Arabidopsis SH3P2 is an ubiquitin-binding protein that functions together with ESCRT-I and the deubiquitylating enzyme AMSH3. Proceedings of the National Academy of Sciences 114 (34), 2017, E7197-E7204 mehr…
Ruprecht, Benjamin; Koch, Heiner; Domasinska, Petra; Frejno, Martin; Kuster, Bernhard; Lemeer, Simone: Optimized Enrichment of Phosphoproteomes by Fe-IMAC Column Chromatography. In: Methods in Molecular Biology. Springer New York, 2017 mehr…
Ruprecht, Benjamin; Wang, Dongxue; Chiozzi, Riccardo Zenezini; Li, Li-Hua; Hahne, Hannes; Kuster, Bernhard: Hydrophilic Strong Anion Exchange (hSAX) Chromatography Enables Deep Fractionation of Tissue Proteomes. In: Methods in Molecular Biology. Springer New York, 2017 mehr…
Ruprecht, Benjamin; Zaal, Esther A.; Zecha, Jana; Wu, Wei; Berkers, Celia R.; Kuster, Bernhard; Lemeer, Simone: Lapatinib Resistance in Breast Cancer Cells Is Accompanied by Phosphorylation-Mediated Reprogramming of Glycolysis. Cancer Research 77 (8), 2017, 1842-1853 mehr…
Ruprecht, Benjamin; Zecha, Jana; Zolg, Daniel P.; Kuster, Bernhard: High pH Reversed-Phase Micro-Columns for Simple, Sensitive, and Efficient Fractionation of Proteome and (TMT labeled) Phosphoproteome Digests. In: Methods in Molecular Biology. Springer New York, 2017 mehr…
Schmidt, Tobias; Samaras, Patroklos; Frejno, Martin; Gessulat, Siegfried; Barnert, Maximilian; Kienegger, Harald; Krcmar, Helmut; Schlegl, Judith; Ehrlich, Hans-Christian; Aiche, Stephan; Kuster, Bernhard; Wilhelm, Mathias: ProteomicsDB. Nucleic Acids Research, 2017 mehr…
Schneider, Katharina S.; Groß, Christina J.; Dreier, Roland F.; Saller, Benedikt S.; Mishra, Ritu; Gorka, Oliver; Heilig, Rosalie; Meunier, Etienne; Dick, Mathias S.; Ćiković, Tamara; Sodenkamp, Jan; Médard, Guillaume; Naumann, Ronald; Ruland, Jürgen; Kuster, Bernhard; Broz, Petr; Groß, Olaf: The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity. Cell Reports 21 (13), 2017, 3846-3859 mehr…
Schott, Ann-Sophie; Behr, Jürgen; Geißler, Andreas J.; Kuster, Bernhard; Hahne, Hannes; Vogel, Rudi F.: Quantitative Proteomics for the Comprehensive Analysis of Stress Responses ofLactobacillus paracaseisubsp.paracaseiF19. Journal of Proteome Research 16 (10), 2017, 3816-3829 mehr…
Stolle, Theresa; Grondinger, Freya; Dunkel, Andreas; Meng, Chen; Médard, Guillaume; Kuster, Bernhard; Hofmann, Thomas: Salivary Proteome Patterns Affecting Human Salt Taste Sensitivity. Journal of Agricultural and Food Chemistry 65 (42), 2017, 9275-9286 mehr…
Werfel, Stanislas; Leierseder, Simon; Ruprecht, Benjamin; Kuster, Bernhard; Engelhardt, Stefan: Preferential microRNA targeting revealed by in vivo competitive binding and differential Argonaute immunoprecipitation. Nucleic Acids Research 45 (17), 2017, 10218-10228 mehr…
Wilhelm, Mathias; Hahne, Hannes; Savitski, Mikhail; Marx, Harald; Lemeer, Simone; Bantscheff, Marcus; Kuster, Bernhard: Wilhelm et al. reply. Nature 547 (7664), 2017, E23-E23 mehr…
Yu, Peng; Petzoldt, Svenja; Wilhelm, Mathias; Zolg, Daniel Paul; Zheng, Runsheng; Sun, Xuefei; Liu, Xiaodong; Schneider, Günter; Huhmer, Andreas; Kuster, Bernhard: Trimodal Mixed Mode Chromatography That Enables Efficient Offline Two-Dimensional Peptide Fractionation for Proteome Analysis. Analytical Chemistry 89 (17), 2017, 8884-8891 mehr…
Zolg, Daniel P; Wilhelm, Mathias; Schnatbaum, Karsten; Zerweck, Johannes; Knaute, Tobias; Delanghe, Bernard; Bailey, Derek J; Gessulat, Siegfried; Ehrlich, Hans-Christian; Weininger, Maximilian; Yu, Peng; Schlegl, Judith; Kramer, Karl; Schmidt, Tobias; Kusebauch, Ulrike; Deutsch, Eric W; Aebersold, Ruedi; Moritz, Robert L; Wenschuh, Holger; Moehring, Thomas; Aiche, Stephan; Huhmer, Andreas; Reimer, Ulf; Kuster, Bernhard: Building ProteomeTools based on a complete synthetic human proteome. Nature Methods 14 (3), 2017, 259-262 mehr…
Zolg, Daniel Paul; Wilhelm, Mathias; Yu, Peng; Knaute, Tobias; Zerweck, Johannes; Wenschuh, Holger; Reimer, Ulf; Schnatbaum, Karsten; Kuster, Bernhard: PROCAL: A Set of 40 Peptide Standards for Retention Time Indexing, Column Performance Monitoring, and Collision Energy Calibration. PROTEOMICS 17 (21), 2017, 1700263 mehr…

2016

Eichner, Ruth; Heider, Michael; Fernández-Sáiz, Vanesa; van Bebber, Frauke; Garz, Anne-Kathrin; Lemeer, Simone; Rudelius, Martina; Targosz, Bianca-Sabrina; Jacobs, Laura; Knorn, Anna-Maria; Slawska, Jolanta; Platzbecker, Uwe; Germing, Ulrich; Langer, Christian; Knop, Stefan; Einsele, Herrmann; Peschel, Christian; Haass, Christian; Keller, Ulrich; Schmid, Bettina; Götze, Katharina S; Kuster, Bernhard; Bassermann, Florian: Immunomodulatory drugs disrupt the cereblon–CD147–MCT1 axis to exert antitumor activity and teratogenicity. Nature Medicine 22 (7), 2016, 735-743 mehr…
Gande, Santosh L.; Saxena, Krishna; Sreeramulu, Sridhar; Linhard, Verena; Kudlinzki, Denis; Heinzlmeir, Stephanie; Reichert, Andreas J.; Skerra, Arne; Kuster, Bernhard; Schwalbe, Harald: Expression and Purification of EPHA2 Tyrosine Kinase Domain for Crystallographic and NMR Studies. ChemBioChem 17 (23), 2016, 2257-2263 mehr…
Groß, Christina J.; Mishra, Ritu; Schneider, Katharina S.; Médard, Guillaume; Wettmarshausen, Jennifer; Dittlein, Daniela C.; Shi, Hexin; Gorka, Oliver; Koenig, Paul-Albert; Fromm, Stephan; Magnani, Giovanni; Ćiković, Tamara; Hartjes, Lara; Smollich, Joachim; Robertson, Avril A.B.; Cooper, Matthew A.; Schmidt-Supprian, Marc; Schuster, Michael; Schroder, Kate; Broz, Petr; Traidl-Hoffmann, Claudia; Beutler, Bruce; Kuster, Bernhard; Ruland, Jürgen; Schneider, Sabine; Perocchi, Fabiana; Groß, Olaf: K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria. Immunity 45 (4), 2016, 761-773 mehr…
Heinzlmeir, S. ; Kudlinzki, D. ; Sreeramulu, S. ; Klaeger, S. ; Gande, S. ; Linhard, V. ; Wilhelm, M. ; Qiao, H. ; Helm, D. ; Ruprecht, B. ; Saxena, K. ; Medard, G. ; Schwalbe, H. ; Kuster, B.: Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs. ACS Chem Biol, 2016 mehr…
Klaeger, Susan; Gohlke, Bjoern; Perrin, Jessica; Gupta, Vipul; Heinzlmeir, Stephanie; Helm, Dominic; Qiao, Huichao; Bergamini, Giovanna; Handa, Hiroshi; Savitski, Mikhail M; Bantscheff, Marcus; Médard, Guillaume; Preissner, Robert; Kuster, Bernhard: Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors. ACS Chemical Biology 11 (5), 2016, 1245-1254 mehr…
Koch, Heiner; Wilhelm, Mathias; Ruprecht, Benjamin; Beck, Scarlet; Frejno, Martin; Klaeger, Susan; Kuster, Bernhard: Phosphoproteome Profiling Reveals Molecular Mechanisms of Growth-Factor-Mediated Kinase Inhibitor Resistance in EGFR-Overexpressing Cancer Cells. Journal of Proteome Research 15 (12), 2016, 4490-4504 mehr…
Lohr, Kerstin; Pachl, Fiona; Moghaddas Gholami, Amin; Geillinger, Kerstin E.; Daniel, Hannelore; Kuster, Bernhard; Klingenspor, Martin: Reduced mitochondrial mass and function add to age‐related susceptibility toward diet‐induced fatty liver in C57BL/6J mice. Physiological Reports 4 (19), 2016, e12988 mehr…
Meng, Chen; Culhane, Aedin: Integrative Exploratory Analysis of Two or More Genomic Datasets. In: Methods in Molecular Biology. Springer New York, 2016 mehr…
Meng, Chen; Helm, Dominic; Frejno, Martin; Kuster, Bernhard: moCluster: Identifying Joint Patterns Across Multiple Omics Data Sets. Journal of Proteome Research 15 (3), 2016, 755-765 mehr…
Meng, Chen; Zeleznik, Oana A.; Thallinger, Gerhard G.; Kuster, Bernhard; Gholami, Amin M.; Culhane, Aedín C.: Dimension reduction techniques for the integrative analysis of multi-omics data. Briefings in Bioinformatics 17 (4), 2016, 628-641 mehr…
Neuhaus, Klaus; Landstorfer, Richard; Fellner, Lea; Simon, Svenja; Schafferhans, Andrea; Goldberg, Tatyana; Marx, Harald; Ozoline, Olga N.; Rost, Burkhard; Kuster, Bernhard; Keim, Daniel A.; Scherer, Siegfried: Translatomics combined with transcriptomics and proteomics reveals novel functional, recently evolved orphan genes in Escherichia coli O157:H7 (EHEC). BMC Genomics 17 (1), 2016 mehr…
Ostrovskyi, Dmytro; Rumpf, Tobias; Eib, Julia; Lumbroso, Alexandre; Slynko, Inna; Klaeger, Susan; Heinzlmeir, Stephanie; Forster, Michael; Gehringer, Matthias; Pfaffenrot, Ellen; Bauer, Silke Mona; Schmidtkunz, Karin; Wenzler, Sandra; Metzger, Eric; Kuster, Bernhard; Laufer, Stefan; Schüle, Roland; Sippl, Wolfgang; Breit, Bernhard; Jung, Manfred: Tofacitinib and analogs as inhibitors of the histone kinase PRK1 (PKN1). Future Medicinal Chemistry 8 (13), 2016, 1537-1551 mehr…
Ruprecht, Benjamin; Roesli, Christoph; Lemeer, Simone; Kuster, Bernhard: MALDI-TOF and nESI Orbitrap MS/MS identify orthogonal parts of the phosphoproteome. PROTEOMICS 16 (10), 2016, 1447-1456 mehr…
Slynko, Inna; Schmidtkunz, Karin; Rumpf, Tobias; Klaeger, Susan; Heinzlmeir, Stephanie; Najar, Abdulkarim; Metzger, Eric; Kuster, Bernhard; Schüle, Roland; Jung, Manfred; Sippl, Wolfgang: Identification of Highly Potent Protein Kinase C-Related Kinase 1 Inhibitors by Virtual Screening, Binding Free Energy Rescoring, and in vitro Testing. ChemMedChem 11 (18), 2016, 2084-2094 mehr…
Steiner, Alexander; Rybak, Katarzyna; Altmann, Melina; McFarlane, Heather E.; Klaeger, Susan; Nguyen, Ngoc; Facher, Eva; Ivakov, Alexander; Wanner, Gerhard; Kuster, Bernhard; Persson, Staffan; Braun, Pascal; Hauser, Marie-Theres; Assaad, Farhah F.: Cell cycle-regulated PLEIADE/AtMAP65-3 links membrane and microtubule dynamics during plant cytokinesis. The Plant Journal 88 (4), 2016, 531-541 mehr…
Strietz, Juliane; Stepputtis, Stella S.; Preca, Bogdan-Tiberius; Vannier, Corinne; Kim, Mihee M.; Castro, David J.; Au, Qingyan; Boerries, Melanie; Busch, Hauke; Aza-Blanc, Pedro; Heynen-Genel, Susanne; Bronsert, Peter; Kuster, Bernhard; Kuster, Bernhard; Stickeler, Elmar; Brabletz, Thomas; Oshima, Robert G.; Maurer, Jochen: ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer. Oncotarget, 2016 mehr…
Treindl, Fridolin; Ruprecht, Benjamin; Beiter, Yvonne; Schultz, Silke; Döttinger, Anette; Staebler, Annette; Joos, Thomas O.; Kling, Simon; Poetz, Oliver; Fehm, Tanja; Neubauer, Hans; Kuster, Bernhard; Templin, Markus F.: A bead-based western for high-throughput cellular signal transduction analyses. Nature Communications 7, 2016, 12852 mehr…
Weigt, David; Hopf, Carsten; Médard, Guillaume: Studying epigenetic complexes and their inhibitors with the proteomics toolbox. Clinical Epigenetics 8 (1), 2016 mehr…
Yu, Peng; Hahne, Hannes; Wilhelm, Mathias; Kuster, Bernhard: Ethylene glycol improves electrospray ionization efficiency in bottom-up proteomics. Analytical and Bioanalytical Chemistry 409 (4), 2016, 1049-1057 mehr…
da Silva, Barbara Ferreira; Meng, Chen; Helm, Dominic; Pachl, Fiona; Schiller, Jürgen; Ibrahim, Emad; Lynne, Charles M.; Brackett, Nancy L.; Bertolla, Ricardo Pimenta; Kuster, Bernhard: Towards Understanding Male Infertility After Spinal Cord Injury Using Quantitative Proteomics. Molecular & Cellular Proteomics 15 (4), 2016, 1424-1434 mehr…

2015

Angelov, Angel; Bergen, Paul; Nadler, Florian; Hornburg, Philipp; Lichev, Antoni; Ãœbelacker, Maria; Pachl, Fiona; Kuster, Bernhard; Liebl, Wolfgang: Novel Flp pilus biogenesis-dependent natural transformation. Frontiers in Microbiology 6, 2015 mehr…
Hao, Yanqi; Colak, Recep; Teyra, Joan; Corbi-Verge, Carles; Ignatchenko, Alexander; Hahne, Hannes; Wilhelm, Mathias; Kuster, Bernhard; Braun, Pascal; Kaida, Daisuke; Kislinger, Thomas; Kim, Philip M.: Semi-supervised Learning Predicts Approximately One Third of the Alternative Splicing Isoforms as Functional Proteins. Cell Reports 12 (2), 2015, 183-189 mehr…
Höfener, Michael; Pachl, Fiona; Kuster, Bernhard; Sewald, Norbert: Inhibitor-based affinity probes for the investigation of JAK signaling pathways. PROTEOMICS 15 (17), 2015, 3066-3074 mehr…
Koch, Heiner; Busto, M. Estela Del Castillo; Kramer, Karl; Médard, Guillaume; Kuster, Bernhard: Chemical Proteomics Uncovers EPHA2 as a Mechanism of Acquired Resistance to Small Molecule EGFR Kinase Inhibition. Journal of Proteome Research 14 (6), 2015, 2617-2625 mehr…
Mergner, Julia; Heinzlmeir, Stephanie; Kuster, Bernhard; Schwechheimer, Claus: DENEDDYLASE1 Deconjugates NEDD8 from Non-Cullin Protein Substrates inArabidopsis thaliana. The Plant Cell 27 (3), 2015, 741-753 mehr…
Médard, Guillaume; Pachl, Fiona; Ruprecht, Benjamin; Klaeger, Susan; Heinzlmeir, Stephanie; Helm, Dominic; Qiao, Huichao; Ku, Xin; Wilhelm, Mathias; Kuehne, Thomas; Wu, Zhixiang; Dittmann, Antje; Hopf, Carsten; Kramer, Karl; Kuster, Bernhard: Optimized Chemical Proteomics Assay for Kinase Inhibitor Profiling. Journal of Proteome Research 14 (3), 2015, 1574-1586 mehr…
Ruprecht, Benjamin; Zecha, Jana; Heinzlmeir, Stephanie; Médard, Guillaume; Lemeer, Simone; Kuster, Bernhard: Evaluation of Kinase Activity Profiling Using Chemical Proteomics. ACS Chemical Biology 10 (12), 2015, 2743-2752 mehr…
Savitski, Mikhail M.; Wilhelm, Mathias; Hahne, Hannes; Kuster, Bernhard; Bantscheff, Marcus: A Scalable Approach for Protein False Discovery Rate Estimation in Large Proteomic Data Sets. Molecular & Cellular Proteomics 14 (9), 2015, 2394-2404 mehr…
Scharow, Andrej; Raab, Monika; Saxena, Krishna; Sreeramulu, Sridhar; Kudlinzki, Denis; Gande, Santosh; Dötsch, Christina; Kurunci-Csacsko, Elisabeth; Klaeger, Susan; Kuster, Bernhard; Schwalbe, Harald; Strebhardt, Klaus; Berg, Thorsten: Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells. ACS Chemical Biology 10 (11), 2015, 2570-2579 mehr…
Schurr, Benjamin C.; Hahne, Hannes; Kuster, Bernhard; Behr, Jürgen; Vogel, Rudi F.: Molecular mechanisms behind the antimicrobial activity of hop iso-α-acids in Lactobacillus brevis. Food Microbiology 46, 2015, 553-563 mehr…

2014

Balluff, Benjamin; Frese, Christian K; Maier, Stefan K; Schöne, Cédrik; Kuster, Bernhard; Schmitt, Manfred; Aubele, Michaela; Höfler, Heinz; Deelder, André M; Heck, Albert JR; Hogendoorn, Pancras CW; Morreau, Johannes; Maarten Altelaar, AF; Walch, Axel; McDonnell, Liam A: De novodiscovery of phenotypic intratumour heterogeneity using imaging mass spectrometry. The Journal of Pathology 235 (1), 2014, 3-13 mehr…
Baumann, Ursula; Fernández-Sáiz, Vanesa; Rudelius, Martina; Lemeer, Simone; Rad, Roland; Knorn, Anna-Maria; Slawska, Jolanta; Engel, Katharina; Jeremias, Irmela; Li, Zhoulei; Tomiatti, Viktoriya; Illert, Anna-Lena; Targosz, Bianca-Sabrina; Braun, Martin; Perner, Sven; Leitges, Michael; Klapper, Wolfram; Dreyling, Martin; Miething, Cornelius; Lenz, Georg; Rosenwald, Andreas; Peschel, Christian; Keller, Ulrich; Kuster, Bernhard; Bassermann, Florian: Disruption of the PRKCD–FBXO25–HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis. Nature Medicine 20 (12), 2014, 1401-1409 mehr…
Breibeck, Joscha; Serafin, Adam; Reichert, Andreas; Maier, Stefan; Küster, Bernhard; Skerra, Arne: PAS-cal: a Generic Recombinant Peptide Calibration Standard for Mass Spectrometry. Journal of The American Society for Mass Spectrometry 25 (8), 2014, 1489-1497 mehr…
Daly, Charlotte E.; Ng, Leong L.; Hakimi, Amirmansoor; Willingale, Richard; Jones, Donald J. L.: Qualitative and Quantitative Characterization of Plasma Proteins When Incorporating Traveling Wave Ion Mobility into a Liquid Chromatography–Mass Spectrometry Workflow for Biomarker Discovery: Use of Product Ion Quantitation As an Alternative Data Analysis Tool for Label Free Quantitation. Analytical Chemistry 86 (4), 2014, 1972-1979 mehr…
Haedke, Ute R.; Frommel, Sandra C.; Hansen, Fabian; Hahne, Hannes; Kuster, Bernhard; Bogyo, Matthew; Verhelst, Steven H. L.: Phosphoramidates as Novel Activity-Based Probes for Serine Proteases. ChemBioChem 15 (8), 2014, 1106-1110 mehr…
Helm, Dominic; Vissers, Johannes P. C.; Hughes, Christopher J.; Hahne, Hannes; Ruprecht, Benjamin; Pachl, Fiona; Grzyb, Arkadiusz; Richardson, Keith; Wildgoose, Jason; Maier, Stefan K.; Marx, Harald; Wilhelm, Mathias; Becher, Isabelle; Lemeer, Simone; Bantscheff, Marcus; Langridge, James I.; Kuster, Bernhard: Ion Mobility Tandem Mass Spectrometry Enhances Performance of Bottom-up Proteomics. Molecular & Cellular Proteomics 13 (12), 2014, 3709-3715 mehr…
Höfener, Michael; Heinzlmeir, Stephanie; Kuster, Bernhard; Sewald, Norbert: Probing SH2-domains using Inhibitor Affinity Purification (IAP). Proteome Science 12 (1), 2014, 41 mehr…
Höfener, Michael; Pachl, Fiona; Take, Tim; Fischer von Mollard, Gabriele; Kuster, Bernhard; Sewald, Norbert: Investigating RET RTK Signaling Pathways Using an IAP-Based Activity-Profiling Approach. Journal of Proteome Research 13 (8), 2014, 3628-3634 mehr…
Ku, Xin; Heinzlmeir, Stephanie; Helm, Dominic; Médard, Guillaume; Kuster, Bernhard: New Affinity Probe Targeting VEGF Receptors for Kinase Inhibitor Selectivity Profiling by Chemical Proteomics. Journal of Proteome Research 13 (5), 2014, 2445-2452 mehr…
Ku, Xin; Heinzlmeir, Stephanie; Liu, Xiaofeng; Médard, Guillaume; Kuster, Bernhard: A new chemical probe for quantitative proteomic profiling of fibroblast growth factor receptor and its inhibitors. Journal of Proteomics 96, 2014, 44-55 mehr…
Lemeer, Simone; Gholami, Amin Moghaddas; Wu, Zhixiang; Kuster, Bernhard: Quantitative proteome profiling of human myoma and myometrium tissue reveals kinase expression signatures with potential for therapeutic intervention. PROTEOMICS 15 (2-3), 2014, 356-364 mehr…
Meng, Chen; Kuster, Bernhard; Culhane, Aedín C; Gholami, Amin: A multivariate approach to the integration of multi-omics datasets. BMC Bioinformatics 15 (1), 2014, 162 mehr…
Médard, Guillaume: A route to the 9,10-secosteroid astrogorgiadiol featuring a key sp2–sp3 Suzuki type cross-coupling. Tetrahedron 70 (2), 2014, 186-196 mehr…
Neumann, Konstantin; Castiñeiras-Vilariño, Mercedes; Höckendorf, Ulrike; Hannesschläger, Nicole; Lemeer, Simone; Kupka, Danny; Meyermann, Svenia; Lech, Maciej; Anders, Hans-Joachim; Kuster, Bernhard; Busch, Dirk H.; Gewies, Andreas; Naumann, Ronald; Groß, Olaf; Ruland, Jürgen: Clec12a Is an Inhibitory Receptor for Uric Acid Crystals that Regulates Inflammation in Response to Cell Death. Immunity 40 (3), 2014, 389-399 mehr…
Pauly, M.; Sroka, M.; Reiss, J.; Rinke, G.; Albarghash, A.; Vogelgesang, R.; Hahne, H.; Kuster, B.; Sesterhenn, J.; Kern, K.; Rauschenbach, S.: A hydrodynamically optimized nano-electrospray ionization source and vacuum interface. The Analyst 139 (8), 2014, 1856 mehr…
Raab, Monika; Krämer, Andrea; Hehlgans, Stephanie; Sanhaji, Mourad; Kurunci-Csacsko, Elisabeth; Dötsch, Christina; Bug, Gesine; Ottmann, Oliver; Becker, Sven; Pachl, Fiona; Kuster, Bernhard; Strebhardt, Klaus: Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1. Molecular Oncology 9 (1), 2014, 140-154 mehr…
Raab, Monika; Pachl, Fiona; Krämer, Andrea; Kurunci-Csacsko, Elisabeth; Dötsch, Christina; Knecht, Rainald; Becker, Sven; Kuster, Bernhard; Strebhardt, Klaus: Quantitative chemical proteomics reveals a Plk1 inhibitor-compromised cell death pathway in human cells. Cell Research 24 (9), 2014, 1141-1145 mehr…
Ruprecht, Benjamin; Koch, Heiner; Medard, Guillaume; Mundt, Max; Kuster, Bernhard; Lemeer, Simone: Comprehensive and Reproducible Phosphopeptide Enrichment Using Iron Immobilized Metal Ion Affinity Chromatography (Fe-IMAC) Columns. Molecular & Cellular Proteomics 14 (1), 2014, 205-215 mehr…
Ruprecht, Benjamin; Lemeer, Simone: Proteomic analysis of phosphorylation in cancer. Expert Review of Proteomics 11 (3), 2014, 259-267 mehr…
Rybak, Katarzyna; Steiner, Alexander; Synek, Lukas; Klaeger, Susan; Kulich, Ivan; Facher, Eva; Wanner, Gerhard; Kuster, Bernhard; Zarsky, Viktor; Persson, Staffan; Assaad, Farhah F.: Plant Cytokinesis Is Orchestrated by the Sequential Action of the TRAPPII and Exocyst Tethering Complexes. Developmental Cell 29 (5), 2014, 607-620 mehr…
Savitski, M. M.; Reinhard, F. B. M.; Franken, H.; Werner, T.; Savitski, M. F.; Eberhard, D.; Molina, D. M.; Jafari, R.; Dovega, R. B.; Klaeger, S.; Kuster, B.; Nordlund, P.; Bantscheff, M.; Drewes, G.: Tracking cancer drugs in living cells by thermal profiling of the proteome. Science 346 (6205), 2014, 1255784-1255784 mehr…
Wilhelm, Mathias; Schlegl, Judith; Hahne, Hannes; Gholami, Amin Moghaddas; Lieberenz, Marcus; Savitski, Mikhail M.; Ziegler, Emanuel; Butzmann, Lars; Gessulat, Siegfried; Marx, Harald; Mathieson, Toby; Lemeer, Simone; Schnatbaum, Karsten; Reimer, Ulf; Wenschuh, Holger; Mollenhauer, Martin; Slotta-Huspenina, Julia; Boese, Joos-Hendrik; Bantscheff, Marcus; Gerstmair, Anja; Faerber, Franz; Kuster, Bernhard: Mass-spectrometry-based draft of the human proteome. Nature 509 (7502), 2014, 582-587 mehr…
Wu, Z. ; Moghaddas, Gholami A. ; Kuster, B.: Systematic identification of the HSP90 regulated proteome. Mol Cell Proteomics., 2014 mehr…
Zourelidou, Melina; Absmanner, Birgit; Weller, Benjamin; Barbosa, Inês CR; Willige, Björn C; Fastner, Astrid; Streit, Verena; Port, Sarah A; Colcombet, Jean; de la Fuente van Bentem, Sergio; Hirt, Heribert; Kuster, Bernhard; Schulze, Waltraud X; Hammes, Ulrich Z; Schwechheimer, Claus: Auxin efflux by PIN-FORMED proteins is activated by two different protein kinases, D6 PROTEIN KINASE and PINOID. eLife 3, 2014 mehr…

2013

Aichler, Michaela; Elsner, Mareike; Ludyga, Natalie; Feuchtinger, Annette; Zangen, Verena; Maier, Stefan K; Balluff, Benjamin; Schöne, Cédrik; Hierber, Ludwig; Braselmann, Herbert; Meding, Stephan; Rauser, Sandra; Zischka, Hans; Aubele, Michaela; Schmitt, Manfred; Feith, Marcus; Hauck, Stefanie M; Ueffing, Marius; Langer, Rupert; Kuster, Bernhard; Zitzelsberger, Horst; Höfler, Heinz; Walch, Axel K: Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria. The Journal of Pathology 230 (4), 2013, 410-419 mehr…
Daniel, Hannelore; Gholami, Amin Moghaddas; Berry, David; Desmarchelier, Charles; Hahne, Hannes; Loh, Gunnar; Mondot, Stanislas; Lepage, Patricia; Rothballer, Michael; Walker, Alesia; Böhm, Christoph; Wenning, Mareike; Wagner, Michael; Blaut, Michael; Schmitt-Kopplin, Philippe; Kuster, Bernhard; Haller, Dirk; Clavel, Thomas: High-fat diet alters gut microbiota physiology in mice. The ISME Journal 8 (2), 2013, 295-308 mehr…
Gholami, Amin Moghaddas; Hahne, Hannes; Wu, Zhixiang; Auer, Florian Johann; Meng, Chen; Wilhelm, Mathias; Kuster, Bernhard: Global Proteome Analysis of the NCI-60 Cell Line Panel. Cell Reports 4 (3), 2013, 609-620 mehr…
Hahne, H. ; Sobotzki, N. ; Nyberg, T. ; Helm, D. ; Borodkin, VS. ; van, Aalten DM. ; Agnew, B. ; Kuster, B.: Proteome wide purification and identification of O-GlcNAc modified proteins using Click chemistry and mass spectrometry. J Proteome Res., 2013 mehr…
Hahne, Hannes; Pachl, Fiona; Ruprecht, Benjamin; Maier, Stefan K; Klaeger, Susan; Helm, Dominic; Médard, Guillaume; Wilm, Matthias; Lemeer, Simone; Kuster, Bernhard: DMSO enhances electrospray response, boosting sensitivity of proteomic experiments. Nature Methods 10 (10), 2013, 989-991 mehr…
Hakenjos, J. P.; Bejai, S.; Ranftl, Q.; Behringer, C.; Vlot, A. C.; Absmanner, B.; Hammes, U.; Heinzlmeir, S.; Kuster, B.; Schwechheimer, C.: ML3 Is a NEDD8- and Ubiquitin-Modified Protein. PLANT PHYSIOLOGY 163 (1), 2013, 135-149 mehr…
Lemeer, S. ; Ruprecht, B. ; Zörgiebel, C. ; Kohl, K. ; Kuster, B.: Comparing immobilized kinase inhibitors and covalent ATP probes for proteomic profiling of kinase expression and drug selectivity. J Proteome Res., 2013 mehr…
Maier, SK. ; Hahne, H. ; Moghaddas, Gholami A. ; Balluff, B. ; Meding, S. ; Schöne, C. ; Walch, A. ; Kuster, B.: Comprehensive identification of proteins from MALDI imaging. Mol Cell Proteomics., 2013 mehr…
Marx, H. ; Lemeer, S. ; Klaeger, S. ; Rattei, T. ; Kuster, B.: MScDB: A Mass Spectrometry Centric Protein Sequence Database for Proteomics. J Proteome Res., 2013 mehr…
Marx, Harald; Lemeer, Simone; Schliep, Jan Erik; Matheron, Lucrece; Mohammed, Shabaz; Cox, Jürgen; Mann, Matthias; Heck, Albert J R; Kuster, Bernhard: A large synthetic peptide and phosphopeptide reference library for mass spectrometry–based proteomics. Nature Biotechnology 31 (6), 2013, 557-564 mehr…
Pachl, Fiona; Plattner, Patrik; Ruprecht, Benjamin; Médard, Guillaume; Sewald, Norbert; Kuster, Bernhard: Characterization of a Chemical Affinity Probe Targeting Akt Kinases. Journal of Proteome Research 12 (8), 2013, 3792-3800 mehr…
Pachl, Fiona; Ruprecht, Benjamin; Lemeer, Simone; Kuster, Bernhard: Characterization of a high field Orbitrap mass spectrometer for proteome analysis. PROTEOMICS 13 (17), 2013, 2552-2562 mehr…
Savitski, MM. ; Mathieson, T. ; Zinn, N. ; Sweetman, G. ; Doce, C. ; Becher, I. ; Pachl, F. ; Kuster, B. ; Bantscheff, M.: Measuring and Managing Ratio Compression for Accurate iTRAQ/TMT Quantification. J Proteome Res., 2013 mehr…
Weis, Corina; Pfeilmeier, Sebastian; Glawischnig, Erich; Isono, Erika; Pachl, Fiona; Hahne, Hannes; Kuster, Bernhard; Eichmann, Ruth; Hückelhoven, Ralph: Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant-powdery mildew interactions. Molecular Plant Pathology 14 (8), 2013, 791-802 mehr…

2012

Bantscheff, M. ; Hobson, S. ; Kuster, B.: Affinity purification of proteins binding to kinase inhibitors immobilized on self-assembling monolayers. Methods Mol Biol. 795, 2012, 149-60 mehr…
Bantscheff, Marcus; Kuster, Bernhard: Quantitative mass spectrometry in proteomics. Analytical and Bioanalytical Chemistry 404 (4), 2012, 937-938 mehr…
Bantscheff, Marcus; Lemeer, Simone; Savitski, Mikhail M.; Kuster, Bernhard: Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present. Analytical and Bioanalytical Chemistry 404 (4), 2012, 939-965 mehr…
Elsner, Mareike; Rauser, Sandra; Maier, Stefan; Schöne, Cédrik; Balluff, Benjamin; Meding, Stephan; Jung, Gerhard; Nipp, Martin; Sarioglu, Hakan; Maccarrone, Giuseppina; Aichler, Michaela; Feuchtinger, Annette; Langer, Rupert; Jütting, Uta; Feith, Marcus; Küster, Bernhard; Ueffing, Marius; Zitzelsberger, Horst; Höfler, Heinz; Walch, Axel: MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma. Journal of Proteomics 75 (15), 2012, 4693-4704 mehr…
Fernández-Sáiz, Vanesa; Targosz, Bianca-Sabrina; Lemeer, Simone; Eichner, Ruth; Langer, Christian; Bullinger, Lars; Reiter, Clemens; Slotta-Huspenina, Julia; Schroeder, Sonja; Knorn, Anna-Maria; Kurutz, Julia; Peschel, Christian; Pagano, Michele; Kuster, Bernhard; Bassermann, Florian: SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma. Nature Cell Biology 15 (1), 2012, 72-81 mehr…
Grüner, BM. ; Hahne, H. ; Mazur, PK. ; Trajkovic-Arsic, M. ; Maier, S. ; Esposito, I. ; Kalideris, E. ; Michalski, CW. ; Kleeff, J. ; Rauser, S. ; Schmid, RM. ; Kuster, B. ; Walch, A. ; Siveke, JT.: MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer. PLoS One. 7 (6), 2012, e39424 mehr…
Hahne, H. ; Gholami, AM. ; Kuster, B.: Discovery of O-GlcNAc-modified proteins in published large-scale proteome data. Mol Cell Proteomics., 2012 mehr…
Hahne, H. ; Kuster, B.: Discovery of O-GlcNAc-6-phosphate-modified proteins by re-analyzing large-scale phosphoproteomics data. Mol Cell Proteomics., 2012 mehr…
Hahne, H. ; Neubert, P. ; Kuhn, K. ; Etienne, C. ; Bomgarden, RD. ; Rogers, JC. ; Kuster, B.: Carbonyl-reactive tandem mass tags for the proteome-wide quantification of N-linked glycans. Anal Chem., 2012 mehr…
Kerner, René; Delgado-Eckert, Edgar; Del Castillo, Estela; Müller-Starck, Gerhard; Peter, Martina; Kuster, Bernhard; Tisserant, Emilie; Pritsch, Karin: Comprehensive proteome analysis in Cenococcum geophilum Fr. as a tool to discover drought-related proteins. Journal of Proteomics 75 (12), 2012, 3707-3719 mehr…
Knapp, Stefan; Arruda, Paulo; Blagg, Julian; Burley, Stephen; Drewry, David H; Edwards, Aled; Fabbro, Doriano; Gillespie, Paul; Gray, Nathanael S; Kuster, Bernhard; Lackey, Karen E; Mazzafera, Paulo; Tomkinson, Nicholas C O; Willson, Timothy M; Workman, Paul; Zuercher, William J: A public-private partnership to unlock the untargeted kinome. Nature Chemical Biology 9 (1), 2012, 3-6 mehr…
Lemeer, S. ; Hahne, H. ; Pachl, F. ; Kuster, B.: Software Tools for MS-Based Quantitative Proteomics: A Brief Overview. Methods Mol Biol. 893, 2012, 489-99 mehr…
Lemeer, S. ; Kunold, E. ; Klaeger, S. ; Raab, M. ; Towers, MW. ; Claudes, E. ; Arrey, TN. ; Strupat, K. ; Urlaub, H. ; Kuster, B.: Phosphorylation site localization in peptides by MALDI MS/MS and the Mascot Delta Score. Anal Bioanal Chem. 402 (1), 2012, 249-60 mehr…
Pachl, Fiona; Fellenberg, Kurt; Wagner, Corinna; Kuster, Bernhard: Ultra-high intra-spectrum mass accuracy enables unambiguous identification of fragment reporter ions in isobaric multiplexed quantitative proteomics. PROTEOMICS 12 (9), 2012, 1328-1332 mehr…
Schirle, Markus; Bantscheff, Marcus; Kuster, Bernhard: Mass Spectrometry-Based Proteomics in Preclinical Drug Discovery. Chemistry & Biology 19 (1), 2012, 72-84 mehr…
Yang, Y. ; Hahne, H. ; Kuster, B. ; Verhelst, SH.: A Simple and Effective Cleavable Linker for Chemical Proteomics Applications. Mol Cell Proteomics., 2012 mehr…
von, Schillde MA. ; Hörmannsperger, G. ; Weiher, M. ; Alpert, CA. ; Hahne, H. ; Bäuerl, C. ; van, Huynegem K. ; Steidler, L. ; Hrncir, T. ; Pérez-Martínez, G. ; Kuster, B. ; Haller, D.: Lactocepin secreted by lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines. Cell Host Microbe. 11 (4), 2012, 387-96 mehr…

2011

Hahne, H. ; Kuster, B.: A Novel Two-Stage Tandem Mass Spectrometry Approach and Scoring Scheme for the Identification of O-GlcNAc Modified Peptides. J Am Soc Mass Spectrom. 22 (5), 2011, 931-42 mehr…
Kramer, K.: Bioassays for estrogenic and androgenic effects of water constituents. In: Treatise on Water Science. Vol. 3. , 2011, 191-219 mehr…
Lemeer, S. ; Bluwstein, A. ; Wu, Z. ; Leberfinger, J. ; Müller, K. ; Kramer, K. ; Kuster, B.: Phosphotyrosine mediated protein interactions of the discoidin domain receptor 1. J Proteomics., 2011 mehr…
Savitski, MM. ; Lemeer, S. ; Boesche, M. ; Lang, M. ; Mathieson, T. ; Bantscheff, M. ; Kuster, B.: Confident phosphorylation site localization using the Mascot Delta Score. Mol Cell Proteomics. 10 (2), 2011, M110.003830 mehr…
Steck, N. ; Hoffmann, M. ; Sava, IG. ; Kim, SC. ; Hahne, H. ; Tonkonogy, SL. ; Mair, K. ; Krueger, D. ; Pruteanu, M. ; Shanahan, F. ; Vogelmann, R. ; Schemann, M. ; Kuster, B. ; Sartor, RB. ; Haller, D.: Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation. Gastroenterology., 2011 mehr…
Wu, Z. ; Doondeea, JB. ; Moghaddas, Gholami A. ; Janning, MC. ; Lemeer, S. ; Kramer, K. ; Eccles, SA. ; Gollin, SM. ; Grenman, R. ; Walch, A. ; Feller, SM. ; Kuster, B.: Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer. Mol Cell Proteomics., 2011 mehr…

2010

Friedrich, L.; Stangl, S.; Hahne, H.; Kuster, B.; Kohler, P.; Multhoff, G.; Skerra, A.: Bacterial production and functional characterization of the Fab fragment of the murine IgG1/ monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics. Protein Engineering Design and Selection 23 (4), 2010, 161-168 mehr…
Gholami, A. M.; Fellenberg, K.: Cross-species common regulatory network inference without requirement for prior gene affiliation. Bioinformatics 26 (8), 2010, 1082-1090 mehr…
Kruse, U; Pallasch, C P; Bantscheff, M; Eberhard, D; Frenzel, L; Ghidelli, S; Maier, S K; Werner, T; Wendtner, C M; Drewes, G: Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells. Leukemia 25 (1), 2010, 89-100 mehr…
Mallick, P. ; Kuster, B.: Proteomics: a pragmatic perspective. Nat Biotechnol. 28 (7), 2010, 695-709 mehr…
Schüller, C. ; Wiebe, JC. ; Pegel, A. ; Kramer, K. ; Skerra, A. ; Hock, B.: A system for repertoire cloning and phage display of murine and leporid antibody fragments. J AOAC Int. 93 (1), 2010, 66-79 mehr…
Wiebe, JC. ; Schüller, C. ; Reiche, JA. ; Kramer, K. ; Skerra, A. ; Hock, B.: An expression system for the E. coli fermentation of recombinant antibody Fab fragments from mice and rabbits. J AOAC Int. 93 (1), 2010, 80-8 mehr…

2009

Mahlknecht, G.; Hock, B.; Kramer, K.: Development of a Monoclonal Antibody for the Detection of a Potentially Allergenic Epitope in Soy. Analytical Letters 43 (1), 2009, 119-132 mehr…

2008

Kramer, K. ; Mahlknecht, G. ; Hock B: Molecular Antibody Technologies for Biosensors and Bioanalytics. In: Handbook of Biosensors and Biochips. John Wiley & Sons, Ltd, 2008 mehr…

2007

Kramer, K. ; Geue, H. ; Hock, B.: Directed evolution of ligand-binding proteins. In: Immunoassay and Other Bioanalytical Techniques. , 2007, 459674 mehr…
Kramer, K. ; Hock, B.: Recombinant Antibodies for Agrochemicals. In: Evolutionary Optimization Rational Environmental Management of Agrochemicals. , 2007, 155-170 mehr…
Kramer, K.; Hubauer, A.; Lausterer, R.; Salvador, J.‐P.; Marco, M.‐P.: Production of Antibodies for the Quantitative Detection of the Anabolically Active Androgens 17β‐Boldenone and Methylboldenone. Analytical Letters 40 (7), 2007, 1461-1472 mehr…

2006

Fellenberg, Kurt; Busold, Christian H; Witt, Olaf; Bauer, Andrea; Beckmann, Boris; Hauser, Nicole C; Frohme, Marcus; Winter, Stefan; Dippon, Jürgen; Hoheisel, Jörg D: BMC Genomics 7 (1), 2006, 319 mehr…
Kaware, M. ; Bronshtein, A. ; Safi, J. ; Van, Emon JM. ; Chuang, JC. ; Hock, B. ; Kramer, K. ; Altstein, M.: Enzyme-linked immunosorbent assay (ELISA) and sol-gel-based immunoaffinity purification (IAP) of the pyrethroid bioallethrin in food and environmental samples. J Agric Food Chem. 54 (18), 2006, 6482-92 mehr…

2005

Cardozo, S. ; González-Techera, A. ; Last, JA. ; Hammock, BD. ; Kramer, K. ; González-Sapienza, GG.: Analyte peptidomimetics selected from phage display peptide libraries: a systematic strategy for the development of environmental immunoassays. Environ Sci Technol. 39 (11), 2005, 4234-41 mehr…
Kramer, K. ; Hock, B.: Molecular basis of toxic effects: Inhibition of cellular pathways and structural components. In: Plant toxicology. , 2005, 331-468 mehr…

2004

Kramer, K. ; Hock, B.: Antibodies for biosensors. In: Ultrathin Electrochemical Chemo- and Biosensors. , 2004, 3 - 22 mehr…

2003

Kramer, K. ; Hock, B.: Recombinant antibodies for environmental analysis. Anal Bioanal Chem. 377 (3), 2003, 417-26 mehr…
Kramer, K. ; Rau, D. ; Hock, B.: Comparison of affinity ranking and immunochemical key data as measure for molecular antibody evolution. Spectroscopy 17 (2-3), 2003, 355-65 mehr…

2002

Hock, B. ; Seifert, M. ; Kramer, K.: Engineering receptors and antibodies for biosensors. Biosens Bioelectron. 17 (3), 2002, 239-49 mehr…
Kramer, K.: Synthesis of a group-selective antibody library against haptens. J Immunol Methods. 266 (1-2), 2002, 209-20 mehr…
Kramer, K.: Evolutionary affinity and selectivity optimization of a pesticide-selective antibody utlizing a hapten-selective immunoglobulin repertoire. Environ Sci Technol. 36 (22), 2002, 4892-8 mehr…
Kramer, K. ; Fiedler, M. ; Skerra, A. ; Hock, B.: A generic strategy for subcloning antibody variable regions from the scFv phage display vector pCANTAB 5 E into pASK85 permits the economical production of F(ab) fragments and leads to improved recombinant immunoglobulin stability. Biosens Bioelectron. 17 (4), 2002, 305-13 mehr…
Loessner, MJ. ; Kramer, K. ; Ebel, F. ; Scherer, S.: C-terminal domains of Listeria monocytogenes bacteriophage murein hydrolases determine specific recognition and high-affinity binding to bacterial cell wall carbohydrates. Mol Microbiol. 44 (2), 2002, 335-49 mehr…
Maqbool, U. ; Anwar-ul-Haq. ; Qureshi, MJ. ; Iqbal, MZ. ; Hock, B. ; Kramer, K.: Development of ELISA technique for the analysis of atrazine residues in water. J Environ Sci Health B. 37 (4), 2002, 307-22 mehr…
Rau, D. ; Kramer, K. ; Hock, B.: Cloning, functional expression and kinetic characterization of pesticide-selective Fab fragment variants derived by molecular evolution of variable antibody genes. Anal Bioanal Chem. 372 (2), 2002, 261-7 mehr…
Rau, D. ; Kramer, K. ; Hock, B.: Single-chain Fv antibody-alkaline phosphatase fusion proteins produced by one-step cloning as rapid detection tools for ELISA. J Immunoassay Immunochem. 23 (2), 2002, 129-43 mehr…

2001

Kramer, K. ; Lepschy, J. ; Hock, B.: Long-term monitoring of atrazine contamination in soil by ELISA. J AOAC Int. 81 (1), 2001, 150-5 mehr…

2000

Hock, Bertold; Kramer, Karl; Seifert, Martin: Environmental Analysis Using Antibody and Receptor Based Techniques. International Journal of Environmental Analytical Chemistry 78 (3-4), 2000, 289-303 mehr…
Rowan, NJ. ; Candlish, AA. ; Bubert, A. ; Anderson, JG. ; Kramer, K. ; McLauchlin, J.: Virulent rough filaments of Listeria monocytogenes from clinical and food samples secreting wild-type levels of cell-free p60 protein. J Clin Microbiol. 38 (7), 2000, 2643-8 mehr…

1999

Hock, B; Rahman, M; Rauchalles, S; Dankwardt, A; Seifert, M; Haindl, S; Kramer, K: Stabilisation of immunoassays and receptor assays. Journal of Molecular Catalysis B: Enzymatic 7 (1-4), 1999, 115-124 mehr…

1998

Kramer, K. ; Knappik, A.: Strategies for recombinant antibody library synthesis: An advanced source for immunoglobulins in environmental analysis. In: Biosensors for Environmental Diagnostics. , 1998, 161-178 mehr…
Kramer, Karl: Synthesis of Pesticide-Specific Single-Chain FVUtilizing the Recombinant Phage Antibody System (RPAS, Pharmacia). A Detailed Protocol. Analytical Letters 31 (1), 1998, 67-92 mehr…

1997

Dankwardt, A.; Kramer, K.; Simon, R.; Freitag, D.; Kettrup, A.; Hock, B.: Nonextractable Pesticide Residues in Humic Substances: Immunochemical Analysis. In: ACS Symposium Series. American Chemical Society, 1997 mehr…
Piehler, Jacob; Brecht, Andreas; Giersch, Thomas; Kramer, Karl; Hock, Bertold; Gauglitz, Günter: Affinity characterization of monoclonal and recombinant antibodies for multianalyte detection with an optical transducer. Sensors and Actuators B: Chemical 39 (1-3), 1997, 432-437 mehr…

1996

Kramer, K. ; Hock, B.: Recombinant antibodies for pesticide immunoanalysis. In: Immunoassays for Residue Analysis. , 1996, 471-484 mehr…
kramer, karl; Hock, Bertold: Recombinant single‐chain antibodies againsts‐Triazines. Food and Agricultural Immunology 8 (2), 1996, 97-109 mehr…

1995

Dankwardt, Andrea; Pullen, Sabine; Rauchalles, Stefanie; Kramer, Karl; Just, Franziska; Hock, Bertold; Hofmann, Ralf; Schewes, Robert; Maidl, Franz Xaver: Atrazine Residues in Soil Two Years After the Atrazine Ban - A Comparison of Enzyme Immunoassay with HPLC. Analytical Letters 28 (4), 1995, 621-634 mehr…
Giersch, T. ; Kramer, K.: Production and application of monoclonal antibodies for the determination of pesticides. In: Immunochemical Detection of Pesticides and Their Metabolites in the Water Cycle. , 1995, 25 - 42 mehr…
Hock, B. ; Giersch, T. ; Kramer, K. ; Dankwardt, A.: Antibody production and progress in hybridoma technology by immunomagnetic screening. In: New Frontiers in Agrochemical Immunoassay. , 1995, 149-162 mehr…
Hock, Bertold; Dankwardt, Andrea; Kramer, Karl; Marx, Alexander: Immunochemical techniques: Antibody production for pesticide analysis. A review. Analytica Chimica Acta 311 (3), 1995, 393-405 mehr…
Piehler, J. ; Brecht, A. ; Kramer, K. ; Hock, B. ; Gauglitz, G.: Multi-analyte determination with a direct optical multi-antibody detection system. In: Environmental Monitoring and Hazardous Waste Site Remediation. , 1995, 185-193 mehr…

1994

Hock, Bertold; Giersch, Thomas; Dankwardt, Andrea; Kramer, Karl; Pullen, Sabine: Toxicity assessment and on-line monitoring: Immunoassays. Environmental Toxicology & Water Quality 9 (4), 1994, 243-262 mehr…
Kramer, Karl; Giersch, Thomas; Hock, Bertold: Magnetic bead selection of hybridomas producing pesticide antibodies. Food and Agricultural Immunology 6 (1), 1994, 5-16 mehr…

1993

Giersch, T. ; Kramer, K. ; Hock, B.: Optimization of a monoclonal antibody-based enzyme immunoassay for the detection of terbuthylazine. Sci Total Environ. 132 (2-3), 1993, 435-48 mehr…
Giersch, T. ; Kramer, K. ; Weller, M. ; Hock, B.: Improvement of a monoclonal antibody-based immunoassay for the determination of terbutryn. Acta hydrochim hydrobiol 21 (6), 1993, 312-5 mehr…
Hock, Bertold; Giersch, Thomas; Kramer, Karl-Josef: Monoclonal antibody-based enzyme immunoassays for the sensitive detection of s-triazines in water. International Conference on Monitoring of Toxic Chemicals and Biomarkers, SPIE, 1993 mehr…