Bartelt Lab
The Bartelt Lab studies metabolic adaptation as a fundamental process by which cells and organisms respond to environmental challenges
- We are particularly interested in the regulation of energy balance, adipocyte health, and obesity associated comorbidities such as type 2 diabetes and cardiovascular disease.
- Our goal is to understand the molecular basis of metabolic biology and find new approaches to tackle metabolic disease clusters.
News
New paper on the impact of intermittent fasting in beta-cell maturation
25 Feb 2025
We are pleased to announce that our latest study has been published in Cell Reports. Our research demonstrates that chronic intermittent fasting impairs beta-cell maturation and function in pre-pubertal mice. This study was led by our co-shared Postdoctoral Researcher Leonardo Matta, under the supervision of Prof. Bartelt and Prof. Herzig at the Helmholtz Institute for Diabetes and Cancer.
Matta, L., Weber, P., Erener, S., Walth-Hummel, A., Hass, D., Bühler, L. K., Klepac, K., Szendroedi, J., Guerra, J., Rohm, M., Sterr, M., Lickert, H., Bartelt, A., & Herzig, S. (2025). Chronic intermittent fasting impairs β cell maturation and function in adolescent mice. Cell reports, 44(2), 115225. Advance online publication. doi.org/10.1016/j.celrep.2024.115225